Results 141 to 150 of about 2,551,121 (363)

Occult Spinal Dysraphism in the Presence of Rare Cutaneous Stigma in a Neonate: Importance of Ultrasound and Magnetic Resonance Imaging

open access: yesCase Reports in Medicine, 2013
Occult spinal dysraphism is defined as a group of dystrophic conditions below an intact cover of dermis and epidermis. Ultrasonography using linear transducers is a fast, inexpensive, and effective method that makes it possible to view the content of the
Claudio Rodrigues Pires   +4 more
doaj   +1 more source

A state-space approach to dynamic tomography

open access: yes, 2010
The statistical inference of a hidden Markov random process is a problem encountered in numerous signal processing applications including dynamic tomography.
Butala, Mark D.
core  

The application of optical coherence tomography to image subsurface tissue structure of Antarctic krill Euphausia superba [PDF]

open access: yes, 2014
Many small open ocean animals, such as Antarctic krill, are an important part of marine ecosystems. To discover what will happen to animals such as krill in a changing ocean, experiments are run in aquaria where conditions can be controlled to simulate ...
Kawaguchi, S.   +46 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Multifrequency methods for Electrical Impedance Tomography

open access: yes, 2015
Multifrequency Electrical Impedance Tomography (MFEIT) is an emerging imaging modality which exploits the dependence of tissue impedance on frequency to recover images of conductivity.
Malone, ER
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Radiologically isolated syndrome as early multiple sclerosis: evolution of diagnostic criteria and management

open access: yesСибирский научный медицинский журнал
Radiologically isolated syndrome (RIS) is currently considered an early preclinical stage of multiple sclerosis (MS). RIS is characterized by typical brain or spinal cord lesions indicative of autoimmune inflammatory demyelination.The aim of the study ...
D. S. Korobko   +5 more
doaj   +1 more source

Optical coherence tomography applied to investigations of optical properties of paintings

open access: yes, 2008
Optical Coherence Tomography (OCT), a fast 3D scanning Michelson interferometer normally applied to biomedical applications has recently been applied to art related subjects.
Peric, B
core  

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