Discerning protein pools by selective staining with self‐labeling tags
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Theranostic approach - promoter of personalised medicine [PDF]
Katerina Kolevska +5 more
doaj +1 more source
Variable Aβ tracer uptake in hyperostosis frontalis interna: implications for brain Aβ PET/CT interpretation. [PDF]
Ryan JM +3 more
europepmc +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Cleaning validation of equipment used for aseptic production of [18F]NaF radiopharmaceutical [PDF]
Marija Atanasova Lazareva +7 more
doaj +1 more source
Use of corneal allogenic intrastromal ring segments (CAIRS) in high astigmatism, a case report. [PDF]
Khayat B, Alabbasi OM, Aljohani G.
europepmc +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Positron Emission Tomography/Computed Tomography Scanner for Pre-Transcatheter Aortic Valve Replacement Assessment: Rethinking Our Resources. [PDF]
Passaniti G +5 more
europepmc +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Ruptured Deep Femoral Artery Aneurysm Caused by Direct Infiltration of Diffuse Large B-Cell Lymphoma. [PDF]
Nakatsu T +7 more
europepmc +1 more source

