Results 201 to 210 of about 2,551,121 (363)

Not All Crescents Are Intramural Hematomas: Differential for Aortic Wall Thickening. [PDF]

JACC Case Rep
Kadoya Y, Boczar KE.
europepmc   +1 more source

Optimal finite element modelling and efficient reconstruction in non-linear 3D electrical resistance tomography

, 2001
Electrical Impedance Tomography can provide images with well-defined characteristics using a fully non-linear reconstruction process when appropriate constraints are imposed on the solution to allow the ill-posed inverse problem to be solved.
Daniell, G.J., Molinari, M., Cox, S.J., Blott, B.H.   +3 more
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Creating a "Box View" of Periprosthetic Distal Femur Fractures Using Three-Dimensional Image Processing. [PDF]

Hawaii J Health Soc Welf
Fithian A, Goodnough LH, DeBaun M, Banta W, Hall K, Amanatullah D, Bishop J, Gardner M.   +7 more
europepmc   +1 more source

Left Ventricular Assist Device Implantation and Aneurysmectomy for a Giant Left Ventricular Aneurysm. [PDF]

JACC Case Rep
Yu W, Chen Z, Liu J.
europepmc   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Unilateral blindness and complete ophthalmoplegia following middle cerebral artery aneurysm clipping: a case report. [PDF]

BMC Ophthalmol
Afshar F, Majd AR, Pourazizi M, Aghajani A, Rafiei A, Sanei P, Khalilian MS.   +6 more
europepmc   +1 more source

Retinal vascular layers imaged by fluorescein angiography and optical coherence tomography angiography.

JAMA ophthalmology, 2015
R. Spaide, J. Klancnik, M. Cooney
semanticscholar   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Progression-free Survival Following Primary Staging with [¹⁸F]PSMA-1007-PET/ceCT Versus Na[¹⁸F]F-PET/ceCT in Prostate Cancer: Results from the PRISMA-PET Randomized Controlled Trial. [PDF]

Eur Urol Open Sci
Buch-Olsen KM, Hansen S, Vilstrup MH, Poulsen MH, Holdgaard PC, Zieger KEA, Asmussen JT, Holm J, Pedersen KT, Hess S, Madsen SS, Eiber M, Gerke O, Hildebrandt MG.   +13 more
europepmc   +1 more source