Results 221 to 230 of about 2,551,121 (363)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Gastroesophageal Junction Adenocarcinoma Presenting With De Novo Metastatic Disease and Ovarian Metastasis in a Young Woman With Atypical Chest Pain. [PDF]

Cureus
Nikolaus Y, Qureshi M.
europepmc   +1 more source

Evaluation of bony fusion after posterior lumbar interbody fusion: a systematic review and meta-analysis. [PDF]

Brain Spine
van Haaster LWF, Mekary RA, Vleggeert-Lankamp CLA.   +2 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Correction: Predicting poor functional outcomes for patients with large computed tomography perfusion core infarctions treated with endovascular thrombectomy. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Role of computed tomography virtual bronchoscopy in a case of pulmonary tuberculosis complicated by bronchopleural fistula and pyopneumothorax. [PDF]

Radiol Case Rep
Miranti PI, Lubis MRS.
europepmc   +1 more source

Significant Response to Nivolumab Plus Ipilimumab in Metastatic Mucinous Tubular and Spindle Cell Carcinoma: A Case Report. [PDF]

IJU Case Rep
Shimasaki S, Yamamoto S, Iguchi M, Yamashita E, Atagi K, Shiba Y, Fukata S, Satake H, Karashima T, Inoue K.   +9 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Acute Neurologic Decline in a Patient With a Headache. [PDF]

J Am Coll Emerg Physicians Open
Pearlmutter J, Warr D.
europepmc   +1 more source