Results 231 to 240 of about 2,386,895 (295)

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Loss of Volatile Metabolites during Concentration of Metabolomic Extracts

ACS Omega
Nataliya A. Osik, Nikita N. Lukzen, Vadim V. Yanshole, Yuri P. Tsentalovich   +3 more
doaj   +1 more source

Bilateral hypoplasia of the intracranial internal carotid arteries: A case report and literature review. [PDF]

Medicine (Baltimore)
Fu W, Zhang C, Liang Y, Deng D.
europepmc   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Construction and application of high-quality development model for public hospitals oriented to regional medical center: an integrated advanced imaging platform for computed tomography, magnetic resonance imaging, and positron emission tomography-computed tomography services. [PDF]

J Appl Clin Med Phys
Zhang Y, Cheng SL, Xu J, Nan BY, Zhou HH.   +4 more
europepmc   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Primary aortic angiosarcoma following endovascular aneurysm repair: Case report and review of the literature. [PDF]

J Vasc Surg Cases Innov Tech
Koussayer S, Almudaiheem FA, Koussayer T, Alkohlani H, Zein N.   +4 more
europepmc   +1 more source

Home Optical Coherence Tomography Monitoring for Neovascular Age-Related Macular Degeneration: Transformative Technology or Cool Toy? [PDF]

Ethan T. Willis, Judy E. Kim, Eric W. Schneider   +2 more
openalex   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Computed Tomography-Guided Biopsy of a Ureteral Urothelial Carcinoma Mimicking a Submucosal Bladder Tumor at the Ureterovesical Junction. [PDF]

IJU Case Rep
Ohtsu A, Fujizuka Y, Arai S, Yamaguchi M, Tokue H, Maehara T, Shimizu T, Sekine Y, Ikota H, Suzuki K.   +9 more
europepmc   +1 more source