Results 101 to 110 of about 35,286 (256)

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Retinex Jointed Multiscale CLAHE Model for HDR Image Tone Compression

Mathematics
Tone-mapping algorithms aim to compress a wide dynamic range image into a narrower dynamic range image suitable for display on imaging devices. A representative tone-mapping algorithm, Retinex theory, reflects color constancy based on the human visual ...
Yu-Joong Kim, Dong-Min Son, Sung-Hak Lee
doaj   +1 more source

High Dynamic Range Mapping for Synthetic Aperture Radar Images

Telfor Journal, 2018
Luminance compression is often performed for high dynamic range images (still images and videos). A nonlinear tone mapping is applied for the compression in order to reproduce high dynamic range images using devices with a more limited (low) dynamic ...
A. Gavrovska, I. Reljin, A. Samčović, M. Milivojević, G. Zajić, V. Starovoitov   +5 more
doaj   +1 more source

A Re-examination of Dichoptic Tone Mapping. [PDF]

ACM Trans Graph, 2021
Wang M, Cooper EA.
europepmc   +1 more source

Application‐Specific Tone Mapping Via Genetic Programming [PDF]

Computer Graphics Forum, 2017
AbstractHigh dynamic range (HDR) imagery permits the manipulation of real‐world data distinct from the limitations of the traditional, low dynamic range (LDR), content. The process of retargeting HDR content to traditional LDR imagery via tone mapping operators (TMOs) is useful for visualizing HDR content on traditional displays, supporting backwards ...
openaire   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Enhanced high dynamic‐range image rendering using a surround map based on edge‐adaptive layer blurring

IET Computer Vision, 2016
Many tone‐mapping methods have developed efficient tone compression and local contrast enhancement techniques for high dynamic‐range imaging. Local tone mapping enhances the image quality to reveal the details; however, it causes artefacts such as halos.
Hyuk‐Ju Kwon, Sung‐Hak Lee, Geun‐Young Lee, Kyu‐Ik Sohng   +3 more
doaj   +1 more source