This study identified a novel PAK2 missense variant, p.Arg350Lys, in a Chinese patient with seizures, nystagmus, and developmental delay. The variant was classified as “likely pathogenic” using ACMG guidelines and showed reduced kinase activity in vitro, particularly affecting Ser141 phosphorylation.
Liwei Shen+4 more
wiley +1 more source
The Effect of 8-Week Protein Supplementation with a Simple Exercise Program on Body Composition, Muscle Strength, and Amino Acid OMICS among Healthy Sedentary Indians: A Randomized, Double-Blind, Placebo-Controlled Trial. [PDF]
Sambashivaiah S+4 more
europepmc +1 more source
Development of a carotenoid enriched probiotic yogurt from fresh biomass of Spirulina and its characterization. [PDF]
Patel P+6 more
europepmc +1 more source
Anti-diabetic prospects of dietary bio-actives of millets and the significance of the gut microbiota: A case of finger millet. [PDF]
Singh V+5 more
europepmc +1 more source
Crossbreeding can enhance genetic diversity and improve herd health and fertility. No practical adverse impacts were detected in Cheddar cheese produced from a typical crossbred system. Jersey‐Holstein‐Friesian and Holstein‐Friesian derived Cheddar showed no significant differences in processing efficiency, nutrition and quality.
Richard M Page+7 more
wiley +1 more source
Interventions to improve vitamin and mineral inadequacies among children in India: a scoping review. [PDF]
Mathias EG+3 more
europepmc +1 more source
Nicotine Decreases Nerve Regeneration and Pain Behaviors via PTEN and Downstream Inflammation-Related Pathway in Two Rat Nerve Injury Models. [PDF]
Fang Y+6 more
europepmc +1 more source
Pilot‐Scale Production of Spray Dried Pulse Protein‐Polyphenol Particles and Protein Bars
ABSTRACT Pulses are still under‐consumed in the USA and in most of the Western world. Scalable, industrially friendly production strategies that deliver good‐tasting pulse ingredients and products are necessary to intensify the use of pulse proteins.
Roberta Targino Hoskin+7 more
wiley +1 more source
ABSTRACT Background The aesthetic issues caused by pigmentation are increasing people's demand for skin whitening. Considering its long‐term use, it is very important for searching safe and effective agents. Pomegranate flower, a kind of traditional Chinese medicine, has shown promising anti‐inflammatory, antioxidant, and antidiabetic properties, but ...
Peng Shu+6 more
wiley +1 more source