Results 71 to 80 of about 757 (185)
Advanced Healthcare Materials, Volume 15, Issue 1, 9 January 2026.A novel blood‐brain barrier‐penetrating terpolymer nanoparticle to deliver brain‐derived neurotrophic factor (BDNF) for the treatment of Alzheimer's disease (AD) is designed. The BDNF‐TPN significantly enhances BDNF accumulation in the brain following intravenous injection, reduces apoptosis and neuroinflammation, thus promoting neuronal survival and ...
Lily Yi Li +8 more
wiley +1 more source
NEAT1 Promotes Epileptogenesis in Tuberous Sclerosis Complex
Advanced Science, Volume 13, Issue 1, 5 January 2026.The primary neurological manifestations of tuberous sclerosis complex (TSC) are intractable epilepsy and intellectual disability. NEAT1 is differentially expressed in TSC‐related epilepsy and influences neuronal excitability by regulating the PI3K/AKT/mTOR signaling pathway.
Suhui Kuang +8 more
wiley +1 more source
Ythdc1‐p300‐Klf5 Complex‐Mediated Golgi Dysfunction Promotes Aortic Aneurysm
Advanced Science, Volume 13, Issue 4, 19 January 2026.In their Research Article (DOI: https://doi.org/10.1002/advs.202512116* lF: 14.1 Q1), Wenli Wang and co‐workers identifies a novel lncRNA m6A modification‐dependent regulatory mechanism of vascular homeostasis, and constructs a predictive model for post‐operative short‐term death based on AD patient's features, providing a platform to be able to ...
Wen‐Li Wang +22 more
wiley +1 more source
Advanced Science, Volume 13, Issue 4, 19 January 2026.This study identifies the circadian transcription factor CLOCK (CLK) as a key regulator of oxidative stress resistance in fruit flies. CLK controls immune responses by driving rhythmic transcription of an RNA‐binding protein‐Achilles (ACHL) in the fly brain, which post‐transcriptionally represses the NF‐κB homolog Relish, limiting immune activation and
Xu Liu +7 more
wiley +1 more source
Green tea catechin loaded niosomes: formulation and their characterization for food fortification. [PDF]
J Food Sci Technol, 2022 Gadapa S +5 more
europepmc +1 more source
Advanced Science, Volume 13, Issue 4, 19 January 2026.Multi‐modal optical imaging reveals microvascular pulsatility in the brain cortex of awake and anaesthetized mice. Awake hemodynamics in male mice are found to be remarkably stable until late life, with flow pulsatility being significantly higher than in females, despite similar average perfusion.
Mia Viuf Skøtt +5 more
wiley +1 more source
Evaluating the impact of an oral nutrition supplement on biochemical profile, growth, and body composition in Indian children: an <i>in-silico</i> study. [PDF]
Front NutrSringari S +6 more
europepmc +1 more source
A Novel SCNN1B Mutation in a Neonate With Systemic Pseudohypoaldosteronism Type 1: Case Report
Clinical Case Reports, Volume 14, Issue 1, January 2026.ABSTRACT Early recognition of PHA1B in neonates with persistent hyperkalemia and hyponatremia is important for timely intervention. Genetic testing confirms the diagnosis, guiding long‐term management. This case highlights a novel SCNN1B mutation, expanding the genetic spectrum and emphasizing the need for lifelong monitoring to prevent life ...
Ensiyeh Bahadoran +2 more
wiley +1 more source
Retail Food Environment in an Urban Resettlement Colony of Delhi: A Community-Based Cross-Sectional Study. [PDF]
Indian J Community MedSeth AK +3 more
europepmc +1 more source
Prefrontal TRPM8 Receptor Modulates Epileptic Seizures via PKA/CREB Signaling Pathway in Mice
CNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.Jia‐zhan Huang et al. describe a function of prefrontal TRPM8 in the regulation of epileptic seizures. TRPM8 receptors was upregulated in the prefrontal cortex (PFC) of epileptic mice. Inhibition or knockdown of TRPM8 in PFC can effectively prolong the latency and reduce the level of seizures in mouse models induced by pentatetrazole. At the same time,
Jia‐Zhan Huang +6 more
wiley +1 more source