Results 31 to 40 of about 5,379,499 (310)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Design of Chatter-Resistant Damped Boring Bars Using a Receptance Coupling Approach
Journal of Manufacturing and Materials Processing, 2020 Deep hole boring using slender bars that have tuned mass dampers integrated within them make the boring process chatter vibration resistant. Dampers are usually designed using classical analytical solutions that presume the (un)damped boring bar which ...
Ajay Yadav +3 more
doaj +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Tangential elastic contact model of the cylindrical contact with different axis crossing angles
Science Progress, 2022 In this paper, a cylinder contact model with different axis crossing angles is proposed, and the axis crossing angle is introduced into the normal and tangential constitutive equations.
Tieneng Guo +3 more
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
DESIGN, DEVELOPMENT AND TESTING OF 4 TOOL AUTOMATIC TOOL CHANGER
, 2017 <p>An automatic tool changer or ATC is used in computerised numerical control (CNC) machine tool to improve the production and tool carrying capacity of the machine. ATC changes the tool very quickly, reducing the non-productive time. Generally, it
DESIGN, DEVELOPMENT AND TESTING OF 4 TOOL AUTOMATIC TOOL CHANGER
core +1 more source
Scientific ReportsThis study aims to provide a new process to improve the welding performance of steel/magnesium dissimilar materials, using an ultrasonic-laser welding-brazing method to joints AZ31B magnesium alloy on 304 stainless steel.
Bing Wang +7 more
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Design of U-Geometry Parameters Using Statistical Analysis Techniques in the U-Bending Process
Metals, 2017 The various U-geometry parameters in the U-bending process result in processing difficulties in the control of the spring-back characteristic. In this study, the effects of U-geometry parameters, including channel width, bend angle, material thickness ...
Wiriyakorn Phanitwong +2 more
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A New Bending Force Formula for the V-Die Bending Process
Metals, 2023 The V-die bending force is an important parameter in respect of press machine capacity selection, but it has not been the focus of previous research. Furthermore, while the various modified formulas proposed in previous research were calculated using V ...
Kongkiet Doungmarda, Sutasn Thipprakmas
doaj +1 more source