Results 51 to 60 of about 5,379,499 (310)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Cool Seq Tool

, 2022
What's Changed ci: bump action versions by @jsstevenson in https://github.com/GenomicMedLab/cool-seq-tool/pull/109 refactor!: rename uta tools to cool seq tool by @korikuzma in https://github.com/GenomicMedLab/cool-seq-tool/pull/110 Staging by ...
Kuzma, Kori, Stevenson, James, Wagner, Alex   +2 more
core   +1 more source

Sidney Machine Tool Company lathe photograph

This photograph shows a lathe at the Sidney Machine Tool Company. Sidney Tool Company was founded in 1905 by Alfred C. Getz in Sidney, Ohio. Getz was also acting plant manager for Monarch Machine Tool, also in Sidney, during the same time.
Sidney Machine Tool Company
core   +2 more sources

Cutting parameter-tool material interaction on PcBN tool wear behaviour in ductile iron machining

Scientific Reports
In response to the increasing requirements for the processing quality and precision of ductile iron parts under the trend of automotive lightweighting and emission reduction, this study systematically investigated the wear behavior and cutting parameter ...
Pengfei Wang, Xiaojing Li, Yongtao Jiu, Huiming Yin, Yingbo Zhang   +4 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Development of comprehensive performance testing technology for motorized spindle

Advances in Mechanical Engineering, 2018
The comprehensive performance test of motorized spindle will contribute to improve the machining quality of machine tool. But existing standards for testing the performance of motorized spindle are limited to test its partial static and dynamic ...
Junwen Wang, Chuangui Yang, Yangqiu Xia, Qiu Hu, Fei Chen, Kun Du   +5 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Tool Unlearning for Tool-Augmented LLMs

CoRR
ICML 2025 https://clu-uml.github.io/MU-Bench-Project-Page/
Jiali Cheng, Hadi Amiri
openaire   +3 more sources

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

WILHELM DILTHEY ON THE OBJECTIVITY OF KNOWLEDGE IN HUMAN SCIENCES [PDF]

Trames, 2007
Andrus Tool
doaj   +1 more source