Results 101 to 110 of about 9,278,986 (351)
PLoS ONE, 2014 BackgroundA combination of clinical and routine laboratory data with biomarkers reflecting different pathophysiological pathways may help to refine risk stratification in heart failure (HF).
Josep Lupón +8 more
doaj +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Predicting corporate failure: empirical evidence for the UK
, 2001 The main purpose of this paper is the development and validation of a failure classification model for UK public industrial companies using current techniques: logit analysis and Neural Networks.
Neophytou, Evridiki +2 more
core
Studies into the Failure Prediction of Brittle Materials [PDF]
, 1987 This thesis is divided into six chapters. The first chapter provides a brief introduction concerning the behaviour of brittle materials. It also contains the justification for the undertaking of the study as well as a brief description of the method ...
Nguyen, P. D.
core
A Fault Prediction Method for CNC Machine Tools Based on SE-ResNet-Transformer
MachinesAiming at the problem that predicted data do not reflect the operating status of computer numerical control (CNC) machine tools, this article proposes a new combined model based on SE-ResNet and Transformer for CNC machine tool failure prediction ...
Zhidong Wu +4 more
doaj +1 more source
Tool failure recognition using inconsistent data
Procedia CIRP, 2022 Júlia Bergmann +3 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Influence of the residual stresses induced by tool wear on the failure of brass electro-valves
, 2013 Failure analysis was performed on different brass electro-valves body affected by unexpected phenomena of cracking. Through the application of optical and scanning electron microscopy, micro hardness Vickers test and X-ray diffraction, the causes of ...
MAPELLI, CARLO +3 more
core
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source