Tool-Path Optimization using Neural Networks [PDF]
Tool-path optimization has been applied in many industrial applications, including subtractive manufacturing likes drilling and additive manufacturing likes 3D printing. The optimization process involves finding a time-efficient route for tools to visit all the required sites, which is often computationally intensive.
Kai-Yin Fok +4 more
openaire +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Novel Tool Path Generation Method for Pocket Machining Using Sound Field Synthesis Theory
Contour parallel tool paths have been proved to be a preferred machining strategy for their advantage of less tool retractions and less sharp turns. The traditional geometrical algorithm-based tool path generation method often makes it hard to simply and
Xuefeng Yang +3 more
doaj +1 more source
Contribution to the Generation of Tool Paths in a Cam System [PDF]
The flank milling of complex forms is a very effective process from the point of view of productivity and surface quality. Many works deal with research on the optimal positioning of the tool which is considered as a rigid body in order to minimize tool path errors.
Larue, Arnaud, Anselmetti, Bernard
openaire +2 more sources
Grain-boundary grooving and agglomeration of alloy thin films with a slow-diffusing species [PDF]
We present a general phase-field model for grain-boundary grooving and agglomeration of polycrystalline alloy thin films. In particular, we study the effects of slow-diffusing species on grooving rate.
D. J. Srolovitz +5 more
core +1 more source
Effects of Biological Sex and Age on Cerebrospinal Fluid Markers—A Retrospective Observational Study
ABSTRACT Objective Cerebrospinal fluid (CSF) analysis is a key diagnostic tool for neurological diseases. To date, only a few studies have investigated in larger cohorts the effect of age and biological sex on diagnostic markers extracted from CSF. Methods For this retrospective observational study, 4163 CSF findings (2012–2020) were evaluated.
Isabel‐Sophie Hafer +3 more
wiley +1 more source
Tool path generation for milling of free form surfaces with feed rate scheduling [PDF]
The use of freeform (sculptured) surfaces in the product design process is accelerating at an exponential rate driven by functional as well as esthetics demands. CAD/CAM software is a must in their design and manufacture.
Mladenović Goran M. +2 more
doaj
Very long optical path-length from a compact multi-pass cell
The multiple-pass optical cell is an important tool for laser absorption spectroscopy and its many applications. For most practical applications, such as trace-gas detection, a compact and robust design is essential.
A. C. Wilson +24 more
core +1 more source
Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi +19 more
wiley +1 more source
Development of multi-pitch tool path in computer-controlled optical surfacing processes
Background Tool path in computer-controlled optical surfacing (CCOS) processes has a great effect on middle spatial frequency error in terms of residual ripples.
Jing Hou, Defeng Liao, Hongxiang Wang
doaj +1 more source

