Results 71 to 80 of about 662,431 (264)

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

Retained Austenite Control for the Soft Machining of High-Hardness Tool Steels

open access: yesMetals, 2018
Most high-hardness tool steels comprising forming dies require expensive finish machining operations to compensate for the dimensional distortion and surface oxidation caused by the die heat treatment.
Maider Muro   +4 more
doaj   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

open access: yesFEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata   +6 more
wiley   +1 more source

Increasing the Wear Resistance of CrWMn Tool Steel Surfaces by Plasma Electrolytic Nitriding and Polishing

open access: yesApplied Sciences
The positive effect of plasma electrolytic treatment on CrWMn tool steel to increase the wear resistance of its surface is shown. The effect of plasma electrolytic nitriding and subsequent polishing on the structure, phase and elemental composition ...
Sergey N. Grigoriev   +8 more
doaj   +1 more source

Interactive industrial application to represent isothermal sections of multi component phase diagram [PDF]

open access: yes, 2019
“Make the slag and the steel will make itself” is an old phrase in steelmaking. The converter or basic oxygen furnace (BOF) process is a necessary step in the steel production during which carbon, phosphorus and other impurities present in the hot metal,
Bellemans, Inge   +4 more
core   +1 more source

Plasma Nitriding of 90CrMoV8 Tool Steel for the Enhancement of Hardness and Corrosion Resistance [PDF]

open access: yes, 2011
The aim of the study is to apply a plasma nitriding process to the 90CrMoV8 steel commonly employed in wood machining, and to determine its efficiency to improve both mechanical and electrochemical properties of the surface.
LAGADRILLERE, Denis   +3 more
core   +3 more sources

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

open access: yesFEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li   +6 more
wiley   +1 more source

Impact of Stress‐Induced Hyperglycemia on In‐Hospital Medical Complications in Patients With Acute Stroke: From a Large‐Scale Nationwide Longitudinal Registry

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Aims This study aimed to explore the relationship between stress‐induced hyperglycemia (SIH) and in‐hospital medical complications in patients with acute stroke. Methods We enrolled 865,765 patients with acute stroke from the Chinese Stroke Center Alliance cohort.
Xintong Song   +6 more
wiley   +1 more source

Nonlinear finite element analysis of reinforced concrete beams strengthened with textile fine grained mortar [PDF]

open access: yes, 2020
Nowadays, there was an increasing need of repairing and upgrading the reinforced concrete (RC) structure due to the deterioration of the structure. The fibre reinforced polymer (FRP) was commonly used for structural retrofitting purposes.
Abdul Hamid, Noor Azlina   +4 more
core  

Thermomechanical modelling of laser surface glazing for H13 tool steel [PDF]

open access: yes, 2018
A two-dimensional thermomechanical finite element (FE) model of laser surface glazing (LSG) has been developed for H13 tool steel. The direct coupling technique of ANSYS 17.2 (APDL) has been utilised to solve the transient thermomechanical process. A H13
BS Yilbas   +23 more
core   +2 more sources

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