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Genetic Aspects of Tooth Agenesis [PDF]

open access: yesGenes
Tooth agenesis is among the most prevalent congenital anomalies affecting human dentition, characterized by the developmental absence of one or more teeth. This condition may be present in either syndromic or non-syndromic forms, with significant implications for oral function, aesthetics, and craniofacial development.
Pietro Chiurazzi   +2 more
exaly   +8 more sources

Occlusal characteristics in modern humans with tooth agenesis [PDF]

open access: yesScientific Reports
Non-syndromic permanent tooth agenesis affects a significant proportion of the population, especially if third molars are considered. Although tooth agenesis has been linked to a smaller craniofacial size, reduced facial convexity and a shorter skeletal ...
Ragda Alamoudi   +4 more
doaj   +9 more sources

Three-dimensional tooth morphology in patients with tooth agenesis and its association to agenesis pattern, severity, and sex [PDF]

open access: yesScientific Reports
Non-syndromic tooth agenesis (TA) can affect both the size and shape of teeth and may interact with sex. This study aimed to advance our understanding of tooth developmental mechanisms by constructing a multifactorial model integrating 3D dental ...
Chihiro Tanikawa   +2 more
doaj   +7 more sources

Advances in tooth agenesis and tooth regeneration. [PDF]

open access: yesRegen Ther, 2023
The lack of treatment options for congenital (0.1%) and partial (10%) tooth anomalies highlights the need to develop innovative strategies. Over two decades of dedicated research have led to breakthroughs in the treatment of congenital and acquired tooth loss.
Ravi V   +9 more
europepmc   +6 more sources

Two novel AXIN2 variants in isolated tooth agenesis and the AXIN2-associated tooth agenesis pattern [PDF]

open access: yesBMC Oral Health
Background Variants in the AXIN2 gene are associated with colorectal cancer, oligodontia-colorectal cancer syndrome, and isolated tooth agenesis. To date, only 19 AXIN2 variants have been linked to tooth agenesis. This study aimed to identify novel AXIN2
Chenxin Geng   +7 more
doaj   +4 more sources

Tooth agenesis review [PDF]

open access: yesČeská Stomatologie a Praktické Zubní Lékařství, 2012
Background: Tooth agenesis means absence or incomplete development of tooth. It is a common human anomaly, which according to Online Mendelian Inheritance in Man database affects approximately 20% of the population.
L. Gábrlíková
doaj   +3 more sources

Patterns of nonsyndromic tooth agenesis and sexual dimorphism [PDF]

open access: yesBMC Oral Health, 2023
Background Sex dimorphism has been implicated in oral health differences and the pathogenesis of oral diseases, such as tooth agenesis, periodontal disease, dental caries, and tooth loss.
Charinya Kanchanasevee   +3 more
doaj   +4 more sources

Tooth agenesis: An overview of diagnosis, aetiology and management [PDF]

open access: yesJapanese Dental Science Review, 2023
Patients with one or more developmentally absent teeth are routinely encountered in dental practice. Tooth agenesis can be associated with significant functional, aesthetic and psycho-social problems.
Maurice J. Meade, Craig W. Dreyer
doaj   +4 more sources

Prevalence and genetic basis of tooth agenesis [PDF]

open access: yesJapanese Dental Science Review, 2009
Tooth agenesis or hypodontia is one of the most common anomalies of the human dentition, characterized by the developmental absence of one or more teeth.
Takehiko Shimizu
exaly   +4 more sources

MMP1 and MMP20 contribute to tooth agenesis in humans [PDF]

open access: yesArchives of Oral Biology, 2011
Variations in genes that are critical for tooth formation may contribute to the tooth agenesis. MMPs are potential candidate genes for dental alterations based on the roles they play during embryogenesis. The aim of this study was to investigate the possible association between MMP1, MMP3, and MMP20 and tooth agenesis.One hundred sixty-seven nuclear ...
Erika Kuchler   +2 more
exaly   +4 more sources

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