Results 31 to 40 of about 6,227 (189)
Research progress on pathogenic genes and molecular mechanisms of nonsyndromic tooth agenesis
口腔疾病防治, 2020 Tooth agenesis is a common tooth number deficiency that occurs in the tooth-forming process or earlier period of tooth germ development and has a serious impact on the maxillofacial development, aesthetics and masticatory function of patients.
XIE Weihong, YU Dongsheng, ZHAO Wei
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Novel WNT10A variant in a Japanese case of nonsyndromic oligodontia
Human Genome Variation, 2023 Congenital tooth agenesis is one of the most common anomalies in humans. Many genetic factors are involved in tooth development, including MSX1, PAX9, WNT10A, and LRP6. Thus, mutations in these genes can cause congenital tooth agenesis in humans. In this
Junya Adachi +15 more
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Effect of Tooth Agenesis on Mandibular Morphology and Position [PDF]
International Journal of Environmental Research and Public Health, 2021 Congenital missing teeth (OMIM #106600) is the most common dental abnormality. The aim of the study was to evaluate the effects of tooth agenesis on the total mandibular length, length of the mandibular body and alveolar process, and the mandibular anteroposterior position.
Agnieszka Jurek +3 more
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Involvement of and interaction between WNT10A and EDA mutations in tooth agenesis cases in the Chinese population. [PDF]
PLoS ONE, 2013 BACKGROUND: Dental agenesis is the most common, often heritable, developmental anomaly in humans. Although WNT10A gene mutations are known to cause rare syndromes associated with tooth agenesis, including onycho-odontodermal dysplasia (OODD), Schöpf ...
Huiying He +6 more
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Estimation of dental age in children in a Turkish population with tooth agenesis
, 2023 Aim: The aim of this study was to investigate tooth development according to chronological age in children with tooth agenesis and to determine whether the severity of tooth agenesis (hypodontia and oligodontia) has an effect on tooth development ...
Zuhal Kirzioglu, Canan Bayraktar Nahir
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Genetic Variants in miRNAs Are Associated With Risk of Non-syndromic Tooth Agenesis
Frontiers in Physiology, 2020 Non-syndromic tooth agenesis (NSTA) is one of the most common dental abnormalities. MiRNAs participated in the craniofacial and tooth development. Therefore, single nucleotide polymorphisms (SNPs) in miRNA genes may contribute to the susceptibility of ...
Min Gu +19 more
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Rare phenotype: Hand preaxial polydactyly associated with LRP6-related tooth agenesis in humans
npj Genomic Medicine, 2021 Low-density lipoprotein receptor-related protein 6 (LRP6) is a pathogenic gene of selective tooth agenesis-7 (OMIM#616724). Although the malformation of the digits and fore- and hindlimbs has been reported in Lrp6-deficient mice, it has been rarely ...
Liutao Zhang +7 more
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Patterns of incisor-premolar agenesis combinations: A retrospective study
Journal of Indian Society of Pedodontics and Preventive Dentistry, 2017 Background: Tooth agenesis is the most common dental anomaly which causes serious problems in humans. Many theories were asserted to explain the main etiologic factor of this anomaly, and genetic factors were considered as primary reasons.
Levent Demiriz +2 more
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The Role of MSX1 in Human Tooth Agenesis [PDF]
Journal of Dental Research, 2002 MSX1 has a critical role in craniofacial development, as indicated by expression assays and transgenic mouse phenotypes. Previously, MSX1 mutations have been identified in three families with autosomal-dominant tooth agenesis. To test the hypothesis that MSX1 mutations are a common cause of congenital tooth agenesis, we screened 92 affected individuals,
A C, Lidral, B C, Reising
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Genetic Variants of BMP2 and Their Association with the Risk of Non-Syndromic Tooth Agenesis. [PDF]
PLoS ONE, 2016 Non-syndromic tooth agenesis (or non-syndromic congenitally missing tooth) is one of the most common congenital defects in humans affecting the craniofacial function and appearance.
Yun Lu +11 more
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