Is Lateral Incisor Agenesis Associated with an Increased Occurrence of Tooth Agenesis Outside of the Cleft Region in Complete Bilateral Cleft Lip and Palate Patients? [PDF]
Iranian Journal of Orthodontics, 2022 Aim: This study compared the prevalence of tooth agenesis out of the cleft area in patients with complete bilateral cleft lip and palate (BCLP) with and without agenesis of maxillary permanent lateral incisors.Methods: Tooth agenesis was evaluated in ...
Daniela Garib +4 more
doaj +1 more source
Dissecting the Genetic Contribution of Tooth Agenesis. [PDF]
Int J Mol SciTooth agenesis (TA), the congenital absence of one or more teeth, is the most common manifestation of defective dental morphogenesis in humans. TA can occur as an isolated (non-syndromic) condition or as part of a broader syndromic presentation. In this review, we analyzed a total of 73 manuscripts to provide a comprehensive update on the genetic ...
Fallea A +7 more
europepmc +3 more sources
Frontiers in Physiology, 2021 Tooth agenesis is a common congenital anomaly in humans and is more common in oral cleft patients than in the general population. Many previous studies suggested that oral cleft and tooth agenesis share a similar genetic background. Therefore, this study
Erika Calvano Küchler +10 more
doaj +1 more source
Subphenotypes in Non-Syndromic Orofacial Cleft Patients Based on the Tooth Agenesis Code (TAC)
Children, 2022 Background: It was the aim of this study to investigate tooth agenesis patterns, which are expressed to different subphenotypes according to the TAC method in a spectrum of non-syndromic orofacial cleft patients.
Dimitrios Konstantonis +3 more
doaj +1 more source
Interaction between IRF6 and TGFA Genes Contribute to the Risk of Nonsyndromic Cleft Lip/Palate [PDF]
, 2012 Previous evidence from tooth agenesis studies suggested IRF6 and TGFA interact. Since tooth agenesis is commonly found in individuals with cleft lip/palate (CL/P), we used four large cohorts to evaluate if IRF6 and TGFA interaction contributes to CL/P ...
Alexandre R. Vieira +18 more
core +10 more sources
TOOTH AGENESIS - THE PROBLEM AND ITS SOLVING IN OUR PRACTICE, PREVALENCE AND RELATION WITH OTHER DEFORMITIES. [PDF]
Journal of IMAB, 2015 Tooth agenesis is an orthodontic abnormality affecting the number of teeth. This leads to various types of malocclusion, disturbance in the masticatory function and poor esthetics. This survey includes 1510 orthodontic patients treated by us.
Greta Yordanova
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Research progress on pathogenic genes and molecular mechanisms of nonsyndromic tooth agenesis
口腔疾病防治, 2020 Tooth agenesis is a common tooth number deficiency that occurs in the tooth-forming process or earlier period of tooth germ development and has a serious impact on the maxillofacial development, aesthetics and masticatory function of patients.
XIE Weihong, YU Dongsheng, ZHAO Wei
doaj +1 more source
Novel WNT10A variant in a Japanese case of nonsyndromic oligodontia
Human Genome Variation, 2023 Congenital tooth agenesis is one of the most common anomalies in humans. Many genetic factors are involved in tooth development, including MSX1, PAX9, WNT10A, and LRP6. Thus, mutations in these genes can cause congenital tooth agenesis in humans. In this
Junya Adachi +15 more
doaj +1 more source
Effect of Tooth Agenesis on Mandibular Morphology and Position [PDF]
International Journal of Environmental Research and Public Health, 2021 Congenital missing teeth (OMIM #106600) is the most common dental abnormality. The aim of the study was to evaluate the effects of tooth agenesis on the total mandibular length, length of the mandibular body and alveolar process, and the mandibular anteroposterior position.
Agnieszka Jurek +3 more
openaire +2 more sources
Functional Study of Ectodysplasin-A Mutations Causing Non-Syndromic Tooth Agenesis. [PDF]
PLoS ONE, 2016 Recent studies have demonstrated that ectodysplasin-A (EDA) mutations are associated with non-syndromic tooth agenesis. Indeed, we were the first to report three novel EDA mutations (A259E, R289C and R334H) in sporadic non-syndromic tooth agenesis.
Wenjing Shen +8 more
doaj +1 more source