D-methionine eradicates Porphyromonas gingivalis biofilms by suppressing the cyclic di-GMP level
Objective To investigate the mechanisms by which D-methionine (D-Met) eradicates Porphyromonas gingivalis biofilms by suppressing cyclic dimeric GMP (c-di-GMP) levels.
XIE Lili +5 more
doaj +1 more source
Meeting report: a hard look at the state of enamel research. [PDF]
The Encouraging Novel Amelogenesis Models and Ex vivo cell Lines (ENAMEL) Development workshop was held on 23 June 2017 at the Bethesda headquarters of the National Institute of Dental and Craniofacial Research (NIDCR).
Bartlett, John D +13 more
core +1 more source
Insights into the Structure and Function of TRIP-1, a Newly Identified Member in Calcified Tissues
Eukaryotic initiation factor subunit I (EIF3i), also called as p36 or TRIP-1, is a component of the translation initiation complex and acts as a modulator of TGF-β signaling. We demonstrated earlier that this intracellular protein is not only exported to
Jaison Arivalagan +4 more
doaj +1 more source
Research progress on the role and mechanism of miR-671 in bone metabolism and bone-related diseases
Bone metabolism consists of bone formation and resorption and maintains a dynamic balance in vivo. When bone homeostasis is broken, it can manifest as osteoarthritis (OA), rheumatoid arthritis (RA), osteosarcoma (OS), etc.
Shaotai Wang +8 more
doaj +1 more source
Background and objectivesPeriodontitis (PD), a chronic inflammatory disease, is a serious threat to oral health and is one of the risk factors for Alzheimer’s disease (AD).
Xiantao Chen +15 more
doaj +1 more source
Antarctic climate, Southern Ocean circulation patterns, and deep water formation during the Eocene [PDF]
We assess early-to-middle Eocene seawater neodymium (Nd) isotope records from seven Southern Ocean deep-sea drill sites to evaluate the role of Southern Ocean circulation in long-term Cenozoic climate change.
Anagnostou +137 more
core +1 more source
Ectopic premolar tooth in the sigmoid notch [PDF]
Impaction of a mandibular premolar is relatively uncommon. Ectopic placement is more unusual and there has been no discussion in the literature of an ectopic mandibular premolar in the coronoid process. In this case report, we present an impacted ectopic
Akgul, Hayati Murat +2 more
core +4 more sources
Harnessing smart nanomaterials to reprogram neutrophil plasticity in immune modulation
Neutrophils are the most abundant type of white blood cells in the immune system and play a complex and intricate regulatory role in disease progression. Their critical contribution to maintaining homeostasis through migration, activation, and programmed
Jiaxin Luo +8 more
doaj +1 more source
Regulation of FN1 degradation by the p62/SQSTM1-dependent autophagy–lysosome pathway in HNSCC
Epithelial–mesenchymal transition (EMT) is involved in both physiological and pathological processes. EMT plays an essential role in the invasion, migration and metastasis of tumours.
Xinchen Liu +8 more
doaj +1 more source
DENTA: A Dual Enzymatic Nanoagent for Self‐Activating Tooth Whitening and Biofilm Disruption
The nanoapatite with dual enzymes (DENTA) accumulates in dentinal tubules, reducing hypersensitivity caused by dental nerve exposure and facilitating continuous ROS generation through salivary glucose for effective, long‐term whitening. The dentin structures remain non‐destructive due to the low concentration of ROS, demonstrating excellent cell ...
Junseok Kim +13 more
wiley +1 more source

