Results 51 to 60 of about 2,966,724 (259)
Energies, 2021 In the case of developing countries, it is not clear which crisis management tools will ensure sustainable development in a sustainable and environmentally friendly way, as well as reducing CO2 emissions in addition to ensuring GDP growth.
Shahjahan Ali +2 more
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FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Information Flow in the Brain: Ordered Sequences of Metastable States
Information, 2017 In this brief overview paper, we analyse information flow in the brain. Although Shannon’s information concept, in its pure algebraic form, has made a number of valuable contributions to neuroscience, information dynamics within the brain is not fully ...
Andrew A. Fingelkurts +1 more
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Adaptation to mis-pronounced speech: evidence for a prefrontal-cortex repair mechanism
Scientific Reports, 2021 Speech is a complex and ambiguous acoustic signal that varies significantly within and across speakers. Despite the processing challenge that such variability poses, humans adapt to systematic variations in pronunciation rapidly.
Esti Blanco-Elorrieta +3 more
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The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
St Andrews Encyclopaedia of Theology, 2023 Causality is a central concept in philosophy and theology and also a basic aspect of human thought and speech. Causal words such as ‘making’, ‘doing’, ‘producing’, and so on, are in constant use.
Michael J. Dodds O.P.
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Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Top-down heterotrophic respiration
, 2019 This file includes top-down estimates of heterotrophic resolution at 4 degrees by 5 degrees spatial resolution and monthly temporal resolution, covering the period January 2010 to December 2012.
Bloom, A. Anthony +11 more
core +1 more source
Evaluation of Polkinghorne's Model Regarding the Mechanism of Divine Action [PDF]
Journal of Philosophical InvestigationsJohn C. Polkinghorne (1930-2021) was one of the leading figures in the field of science and theology, who had a distinctive approach to explaining the mechanism of divine action in the natural world.
Mohammad-Ebrahim Maghsoudi +1 more
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