Results 81 to 90 of about 2,966,724 (259)

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi   +8 more
wiley   +1 more source

Síndrome de Down y homosexualidad [PDF]

open access: yes, 2012
La persona con síndrome de Down y homosexual sufre una doble discriminación. una por su discapacidad y otra por su orientación sexual. Además dentro del mundo de la homosexualidad, al igual que en la sociedad en la que vivimos, se da una gran ...
García, José Luis
core  

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

Information and Life: Towards a Biological Understanding of Informational Phenomena

open access: yestripleC: Communication, Capitalism & Critique, 2008
This work explores a new understanding of informational phenomena based on the molecular organization of life. One of the central ideas is that the interrelationship among the recently framed fields of genomics, proteomics, and signaling science (crucial
Pedro C. Marijuán
doaj   +1 more source

Acute Kidney Injury After Mechanical Thrombectomy for Stroke in Patients With Pre‐Existing Renal Impairment

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Acute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre‐existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high‐risk population.
Michał Borończyk   +10 more
wiley   +1 more source

Top-down view CoM and CoP.

open access: yes, 2023
Top-down view of the centre of mass (CoM in red) and centre of pressure (CoP in blue) trajectories after a 9% magnitude perturbation given in the direction indicated in the middle of the figure.
Michelle van Mierlo (15213490)   +4 more
core   +1 more source

An evaluation of the current urban design process in order to derive critical success factors for the creation of a potential new urban design process framework [PDF]

open access: yes, 2015
The current urban design process is top-down, i.e., generally the urban designers or planners design the urban environment and at a later stage the community may have some involvement. There are serious criticisms of this process as it may not touch the “
Dias, Nuwan   +3 more
core   +3 more sources

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng   +4 more
wiley   +1 more source

LC-MS proteomic characterization of TgCRND8 AD model mice brain tissue following the top-down approach

open access: yes, 2016
LC-MS proteomic characterization of TgCRND8 AD model mice brain tissue following the top-down ...
DV Rossetti   +10 more
core  

Use of top-down and bottom-up fourier transform ion cyclotron resonance mass spectrometry for mapping calmodulin sites modified by platinum anticancer drugs [PDF]

open access: yes, 2011
Calmodulin (CaM) is a highly conserved, ubiquitous, calcium-binding protein; it binds to and regulates many different protein targets, thereby functioning as a calcium sensor and signal transducer.
Lin, Tzu-Yung   +17 more
core   +1 more source

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