Results 111 to 120 of about 236,582 (260)

Inconsistent effects of P enrichment and predator presence on food‐web dynamics in a bromeliad system

open access: yesOikos, EarlyView.
Food webs consist of trophic interactions of variable strength. However, it remains challenging to predict how changes in environmental conditions, such as nutrient enrichment, can affect these interactions. In this paper, we propose to integrate food web theory with ecological stoichiometry, which predicts how elemental ratios affect trophic ...
Pierre Rogy   +6 more
wiley   +1 more source

Comprehensive Surrogate Models for Predicting the Melt Conveying Characteristics of Channel Segments in High‐Performance Single‐Screw Extruders

open access: yesPolymer Engineering &Science, EarlyView.
Generalized analytical equations were developed that accurately predict the local pumping characteristics, viscous dissipation, and average shear rates in channels of both conventional and high‐performance single‐screw extruders. Applied within segmented extruder calculations, these models aid in screw design and process troubleshooting without the ...
Daniel Herzog   +3 more
wiley   +1 more source

Nigericin‐Triggered Phosphodynamics in Inflammasome Formation and Pyroptosis

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Innate immune signaling relies heavily on phosphorylation cascades to mount effective immune responses. Although traditional innate immune signaling cascades following TLR4 stimulation have been investigated through a temporally quantitative phosphoproteomic lens, far fewer studies have applied these methods to distinct signaling following the
Vanya Bhushan   +5 more
wiley   +1 more source

Detecting and attributing climate change effects on vegetation: Australia as a test case

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
Climate change is contributing to vegetation changes that threaten life support systems. Yet, inherent climatic variability and past and present human actions—such as clearing, burning and grazing regimes—also alter vegetation and complicate understanding of vegetation change. Australian ecosystems exemplify such complexity.
Laura J. Williams   +14 more
wiley   +1 more source

Snapshots of Motion: A Novel Structural Intermediate Reveals Conserved Dynamics in Archaeal DNA Ligases

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT We present the first x‐ray crystallographic structural evidence of an archaeal DNA ligase showing the AMP covalent adduct together with further cofactor hydrolysis, capturing a transient intermediary in the first step of the ligation reaction, triggered by the pyrophosphate hydrolysis.
A. X. Quintana‐Armas   +3 more
wiley   +1 more source

A Generalized Minimal PBPK‐PD Model of Bispecific Antibodies: Case Studies and Applications in Drug Development

open access: yesCPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Bispecific antibodies (bsAbs), for which each arm binds a distinct molecular target, are developed to engage soluble and cell surface targets in different therapeutic indications. Three key examples of mechanisms of action (MoA) for bsAbs are (1) immune cell engagers that foster immune cell interactions with target cells, (2) bispecifics that ...
Phillip Spinosa   +4 more
wiley   +1 more source

CONCERT: A Modular Reconfigurable Robot for Construction

open access: yesJournal of Field Robotics, EarlyView.
ABSTRACT This paper presents CONCERT, a fully reconfigurable modular collaborative robot (cobot) for multiple on‐site operations in a construction site. CONCERT has been designed to support human activities in construction sites by leveraging two main characteristics: high‐power density motors and modularity. In this way, the robot is able to perform a
Luca Rossini   +18 more
wiley   +1 more source

Why Autonomous Vehicles Are Not Ready Yet: A Multi‐Disciplinary Review of Problems, Attempted Solutions, and Future Directions

open access: yesJournal of Field Robotics, EarlyView.
ABSTRACT Personal autonomous vehicles can sense their surrounding environment, plan their route, and drive with little or no involvement of human drivers. Despite the latest technological advancements and the hopeful announcements made by leading entrepreneurs, to date no personal vehicle is approved for road circulation in a “fully” or “semi ...
Xingshuai Dong   +13 more
wiley   +1 more source

Applying computer vision to accelerate monitoring and analysis of bird incubation behaviors: a case study using common eider nest camera footage

open access: yesRemote Sensing in Ecology and Conservation, EarlyView.
Visualization of the pipeline is divided into two primary segments: automated (i.e., the user adapts the code directly to build a custom computer vision model) and human‐in‐the‐loop (i.e., the user manually evaluates the output of the model). In step 1, raw imagery data are selected for training and testing datasets; ideally, these datasets are ...
Lindsay Veazey   +3 more
wiley   +1 more source

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