Results 131 to 140 of about 2,336,780 (253)

Childhood adversity and psychotic‐like experiences in adolescence: Investigating a pathway via disrupted pubertal and grey matter development

open access: yesJCPP Advances, EarlyView.
Abstract Background Childhood adversity increases psychosis risk, but the biological mechanisms responsible remain elusive. A possible but underexplored pathway involves altered pubertal and grey matter (GM) development. Methods In youth from the Adolescent Brain Cognitive Development study (N = 3462), we investigated the effect of adversity at age 9 ...
Megan Thomas   +3 more
wiley   +1 more source

Bottom-up/Top-Down Image Parsing by Attribute Graph Grammar

open access: yes, 2008
In this paper, we present an attribute graph grammar for image parsing on scenes with man-made objects, such as buildings, hallways, kitchens, and living rooms.

core  

Higher Energy Demands and Lower Body Condition in a Hot Spring: Comparing Relict Leopard Frogs at Two Thermally Contrasting Sites

open access: yesJournal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT Following range‐wide decline, all remnant populations of the relict leopard frog (Rana onca) in the eastern Mojave Desert of the southwestern USA occupied geothermally influenced hot springs. In recent years, however, several large populations have been established at cold‐water sites.
Robert P. Pelletier   +3 more
wiley   +1 more source

Revisiting the Intellectual Legacy of H. Igor Ansoff: A Critical Analysis of His Contributions and Their Impact on the Evolution of Strategic Management

open access: yesStrategic Change, EarlyView.
ABSTRACT This systematic review examines how H. Igor Ansoff's theoretical contributions have evolved in contemporary strategic management through cluster analysis of 116 publications (1968–2024). Four distinct research clusters were identified, revealing that Ansoff's legacy has shifted from theoretical foundations to pedagogical applications and ...
Adiemir Hortega   +4 more
wiley   +1 more source

Mapping Causal Biology: Mendelian Randomization in the Era of Big Data

open access: yesMed Research, EarlyView.
Mendelian randomization (MR) leverages genetic variants to mitigate confounding biases in causal inference. This review systematically maps MR's methodological evolution, highlights its expanding applications in epidemiology and drug target validation, and outlines future directions for overcoming current biases through dynamic, multi‐omics, and cross ...
Xuanlu Shen   +10 more
wiley   +1 more source

Female cortical cellular mosaicism underlies shared MeCP2 and PCB impacted gene pathways. [PDF]

open access: yesiScience
Sharifi O   +7 more
europepmc   +1 more source

AI‐Driven Synthesis in Medicinal Chemistry: Integrating Large Language Models, Robotic Automation, and Sustainability Metrics to Accelerate Drug Discovery

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Artificial intelligence (AI) is transforming synthetic chemistry from task‐specific predictors into integrated platforms that unify retrosynthesis, reaction optimization, and closed‐loop robotic automation. This review highlights how AI‐assisted planning and robotic execution shorten cycle times, reduce step counts, and improve route ...
Amit Gangwal, Antonio Lavecchia
wiley   +1 more source

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