Results 191 to 200 of about 9,334,973 (302)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

SWOOP: top-k similarity joins over set streams. [PDF]

VLDB J
Mann W, Augsten N, Jensen CS, Pawlik M.
europepmc   +1 more source

K-State First Co-Curricular Guide 2019

, 2019
Citation: K-State First (2019). K-State First Co-Curricular Guide 2019. Manhattan, Kansas: K-State First.Co-curricular events have a huge impact on student learning and community building. Students often note that they remember these out of the classroom
Kansas State University, K-State First
core  

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

ATDMNet: Multi-Head Agent Attention and Top-k Dynamic Mask for Camouflaged Object Detection. [PDF]

Sensors (Basel)
Fu R, Li Y, Chen CC, Duan Y, Yao P, Zhou K.   +5 more
europepmc   +1 more source

Top-k Document Ranking and Sentence Similarity Retrieval System for Covid-19 Research Papers

, 2022
Adesokan A.
europepmc   +1 more source

Where to search top-K biomedical ontologies? [PDF]

Brief Bioinform, 2019
Oliveira D, Butt AS, Haller A, Rebholz-Schuhmann D, Sahay R.   +4 more
europepmc   +1 more source

Sensitivity index to measure dependence on parameters for rankings and top-k rankings. [PDF]

J Appl Stat, 2020
Rolland A, Cugliari J.
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

On O ( n ) algorithms for projection onto the top- k -sum sublevel set. [PDF]

Math Program Comput
Roth J, Cui Y.
europepmc   +1 more source