Results 111 to 120 of about 3,873,151 (300)
Text Mining and Topic Modeling in Education: Revealing Insights From Educational Textual Data
This book chapter explores the transformative potential of text mining and topic modeling in the field of education. With the exponential growth of digital educational content, the need for effective analysis and understanding of large-scale textual data
Sabamehr, M., Ekin, C.Ç.
core +1 more source
Topic Modeling and its Applications
, 2021 vii, 28 p.The amount of data online is growing rapidly, and while most people think about numbers when they hear data, there is a huge amount of textual data available that can prove to be useful.
Devine, Nolan
core +1 more source
Research Community Mining via Generalized Topic Modeling [PDF]
Mehran University Research Journal of Engineering and Technology, 2012 Mining research community on the basis of hidden relationships present between its entities is important from academic recommendation point of view. Previous approaches discovered research community by using network connectivity based distance measures
Ali Daud +2 more
doaj
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Automatic Seed Word Selection for Topic Modeling
IEEE AccessTopic modeling is widely used to uncover latent semantic topics from a corpus. However, topic models often struggle to identify minor topics due to their tendency to prioritize dominant patterns in the data. They are also hindered by polysemous words and
Dahyun Jeong +3 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Functional similarities between bimanual coordination and topic/comment structure [PDF]
, 2007 Human manual action exhibits a differential use of a non-dominant (typically, left) and a dominant (typically, right) hand. Human communication exhibits a pervasive structuring of utterances into topic and comment.
Manfred Krifka, Krifka, Manfred
core +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source