Results 171 to 180 of about 1,022,373 (272)

Topics in Mathematical Modeling [PDF]

, 2007
Ka Kit Tung
openalex   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Women are under-represented in adaptation policy research and are more likely to emphasise justice topics

Environmental Research: Climate
This paper is the first to analyse the role of women authors in fostering justice-relevant topics in climate adaptation research. As representation, citation and payment patterns remain gender-biased across scientific disciplines, we explore the case of ...
Diana Danilenko, Marina Andrijevic, Anne J Sietsma, Max Callaghan, Tarun Khanna   +4 more
doaj   +1 more source

Robust topic inference for latent semantic language model adaptation [PDF]

, 2007
Aaron Heidel, Lin-Shan Lee
openalex   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Qualitative Insights Tool (QualIT): LLM Enhanced Topic Modeling [PDF]

arXiv
Topic modeling is a widely used technique for uncovering thematic structures from large text corpora. However, most topic modeling approaches e.g. Latent Dirichlet Allocation (LDA) struggle to capture nuanced semantics and contextual understanding required to accurately model complex narratives.
arxiv  

Three Topics on Statistical Analysis. Regression to the Mean, Multilevel Statistical Models, and Poisson Regression.

, 2001
Shoji Tokunaga
openalex   +2 more sources

Topics in Ultra-cold Bose Gases: the Bose-Hubbard Model; Analogue Models for an Expanding Universe and for an Acoustic Black Hole [PDF]

, 2007
Piyush Jain
openalex   +1 more source

CD44v, S1PR1, HER3, MET and cancer‐associated amino acid transporters are promising targets for the pancreatic cancers characterized using mAb

FEBS Open Bio, EarlyView.
Novel mAbs could detect cancer‐associated membrane proteins on various type of pancreatic ductal adenocarcinomas (PDAC) by flow cytometry with viable PDAC cells and by immunohistochemistry with PDAC tissues. Results of protein expression were substantiated by mRNA expression by The Cancer Genome Atlas.
Takashi Nakano, Kouki Okita, Shogo Okazaki, Soshi Yoshimoto, Sachiko Masuko, Hideki Yagi, Kazunori Kato, Yoshihisa Tomioka, Kenichi Imai, Yoichi Hamada, Kazue Masuko, Kayoko Shimada‐Takaura, Noriaki Nagai, Hideyuki Saya, Tomio Arai, Toshiyuki Ishiwata, Takashi Masuko   +16 more
wiley   +1 more source

Modeling Dynamic Topics in Chain-Free Fashion by Evolution-Tracking Contrastive Learning and Unassociated Word Exclusion [PDF]

arXiv
Dynamic topic models track the evolution of topics in sequential documents, which have derived various applications like trend analysis and opinion mining. However, existing models suffer from repetitive topic and unassociated topic issues, failing to reveal the evolution and hindering further applications.
arxiv