Results 191 to 200 of about 637,325 (290)

Age-dependent topic modelling of comorbidities in UK Biobank identifies disease subtypes with differential genetic risk

, 2022
Jiang X, McVean G, Price AL, Zhang M, Zhang Y, Inouye M, Holmes C.   +6 more
europepmc   +2 more sources

The quality and scope of health information on online drug platforms: a topic modelling and expert evaluation study of a Polish-language forum. [PDF]

Harm Reduct J
Siuda P, Matuszewski P.
europepmc   +1 more source

Using topic modelling for unsupervised annotation of electronic health records to identify an outbreak of disease in UK dogs. [PDF]

PLoS One, 2021
Noble PM, Appleton C, Radford AD, Nenadic G.   +3 more
europepmc   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

Scalable topic modelling decodes spatial tissue architecture for large-scale multiplexed imaging analysis. [PDF]

Nat Commun
Peng X, Smithy JW, Yosofvand M, Kostrzewa CE, Bleile M, Ehrich FD, Lee J, Postow MA, Callahan MK, Panageas KS, Shen R.   +10 more
europepmc   +1 more source

Age-dependent topic modeling of comorbidities in UK Biobank identifies disease subtypes with differential genetic risk. [PDF]

Nat Genet, 2023
Jiang X, Zhang MJ, Zhang Y, Durvasula A, Inouye M, Holmes C, Price AL, McVean G.   +7 more
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Guests' Aesthetic experience with lifestyle hotels: An application of LDA topic modelling analysis. [PDF]

Heliyon
Ying S.
europepmc   +1 more source

Semantic Analysis and Topic Modelling of Web-Scrapped COVID-19 Tweet Corpora through Data Mining Methodologies. [PDF]

Healthcare (Basel), 2022
Gourisaria MK, Chandra S, Das H, Patra SS, Sahni M, Leon-Castro E, Singh V, Kumar S.   +7 more
europepmc   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source