Results 171 to 180 of about 637,325 (290)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Identifying barriers to human papillomavirus vaccination in China: a topic modelling analysis of social media (2018-2024). [PDF]

BMJ Public Health
Ding Z, Yang H, Zhou Y, Wang C, Ma L, Ren K, Hou Z.   +6 more
europepmc   +1 more source

The barriers and enablers to downloading the COVIDSafe app - a topic modelling analysis. [PDF]

Aust N Z J Public Health, 2021
Smoll NR, Walker J, Khandaker G.
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Mapping of Subjective Accounts into Interpreted Clusters (MOSAIC): Topic Modelling and LLM applied to Stroboscopic Phenomenology. [PDF]

Neurosci Conscious
Beauté R, Schwartzman DJ, Dumas G, Crook J, Macpherson F, Barrett AB, Seth AK.   +6 more
europepmc   +1 more source

Gender Bias in the News: A Scalable Topic Modelling and Visualization Framework. [PDF]

Front Artif Intell, 2021
Rao P, Taboada M.
europepmc   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Capturing the experiences of UK healthcare workers during the COVID-19 pandemic: A structural topic modelling analysis of 7,412 free-text survey responses. [PDF]

PLoS One, 2022
Lamb D, Wright L, Scott H, Croak B, Gnanapragasam S, Docherty M, Greenberg N, Hotopf M, Stevelink SAM, Raine R, Wessely S.   +10 more
europepmc   +2 more sources

Thematic landscapes and temporal trends of disability technology adoption: insights from Structural Topic Modelling. [PDF]

Front Digit Health
Kiruthiga M, Vivek Raj SN.
europepmc   +1 more source

Mapping research on healthcare operations and supply chain management: a topic modelling-based literature review. [PDF]

Ann Oper Res, 2022
Ali I, Kannan D.
europepmc   +1 more source