Results 71 to 80 of about 61,609 (261)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
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Jurnal SisfokomBiomedical research has become an essential entity in human life. However, finding trends related to research topics in the health sector contained in the repository is a challenging matter.
Yuri Pamungkas
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FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
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Unsupervised learning and natural language processing highlight research trends in a superbug
Frontiers in Artificial IntelligenceIntroductionAntibiotic-resistant Acinetobacter baumannii is a very important nosocomial pathogen worldwide. Thousands of studies have been conducted about this pathogen. However, there has not been any attempt to use all this information to highlight the
Carlos-Francisco Méndez-Cruz +4 more
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Two-stage topic modelling of scientific publications: A case study of University of Nairobi, Kenya.
PLoS ONE, 2021 Unsupervised statistical analysis of unstructured data has gained wide acceptance especially in natural language processing and text mining domains. Topic modelling with Latent Dirichlet Allocation is one such statistical tool that has been successfully ...
Leacky Muchene, Wende Safari
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Efficient Correlated Topic Modeling with Topic Embedding [PDF]
Proceedings of the 23rd ACM SIGKDD International Conference on Knowledge Discovery and Data Mining, 2017 KDD 2017 oral.
Junxian He +4 more
openaire +2 more sources
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
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Secure latent Dirichlet allocation
Frontiers in Digital HealthTopic modelling refers to a popular set of techniques used to discover hidden topics that occur in a collection of documents. These topics can, for example, be used to categorize documents or label text for further processing. One popular topic modelling
Thijs Veugen +4 more
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
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BuildingsThe COVID-19 pandemic was a particularly challenging time for the construction industry as it experienced significant disruptions to operations, affecting various stakeholders.
Emmanuel B. Boateng +3 more
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