Results 81 to 90 of about 637,325 (290)

Learning Reputation in an Authorship Network

open access: yes, 2013
The problem of searching for experts in a given academic field is hugely important in both industry and academia. We study exactly this issue with respect to a database of authors and their publications.
Clémençon, Stéphan   +1 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Emotion-affected decision making in human simulation [PDF]

open access: yes, 2006
Human modelling is an interdisciplinary research field. The topic, emotion-affected decision making, was originally a cognitive psychology issue, but is now recognized as an important research direction for both computer science and biomedical modelling.
Kang, J, Wright, D K, Zhao, Y
core  

Ms2lda.org: web-based topic modelling for substructure discovery in mass spectrometry [PDF]

open access: yes, 2017
Motivation: We recently published MS2LDA, a method for the decomposition of sets of molecular fragment data derived from large metabolomics experiments.
Barrett, Michael P.   +5 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Unsupervised learning and natural language processing highlight research trends in a superbug

open access: yesFrontiers in Artificial Intelligence
IntroductionAntibiotic-resistant Acinetobacter baumannii is a very important nosocomial pathogen worldwide. Thousands of studies have been conducted about this pathogen. However, there has not been any attempt to use all this information to highlight the
Carlos-Francisco Méndez-Cruz   +4 more
doaj   +1 more source

Hybrid process modelling within business process management projects [PDF]

open access: yes, 2010
Business Process Management (BPM) is still an important research topic amongst both academics and businesses. The recent recession has forced businesses to focus on cost control and efficiency in order to better cope with the economic downturn.
Cull, R, Eldabi, T
core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Secure latent Dirichlet allocation

open access: yesFrontiers in Digital Health
Topic modelling refers to a popular set of techniques used to discover hidden topics that occur in a collection of documents. These topics can, for example, be used to categorize documents or label text for further processing. One popular topic modelling
Thijs Veugen   +4 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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