Results 81 to 90 of about 1,022,373 (272)

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

open access: yesMolecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi   +6 more
wiley   +1 more source

Extractive Automatic Text Summarization Based on Lexical-Semantic Keywords

open access: yesIEEE Access, 2020
The automatic text summarization (ATS) task consists in automatically synthesizing a document to provide a condensed version of it. Creating a summary requires not only selecting the main topics of the sentences but also identifying the key relationships
Angel Hernandez-Castaneda   +3 more
doaj   +1 more source

Topic Classification of Central Bank Monetary Policy Statements: Evidence from Latent Dirichlet Allocation in Lesotho

open access: yesActa Universitatis Sapientiae: Economics and Business, 2022
This article develops a baseline on how to analyse the statements of monetary policy from Lesotho’s Central Bank using a method of topic classification that utilizes a machine learning algorithm known as Latent Dirichlet Allocation.
Damane Moeti
doaj   +1 more source

Neural Topic Modeling with Cycle-Consistent Adversarial Training [PDF]

open access: yesarXiv, 2020
Advances on deep generative models have attracted significant research interest in neural topic modeling. The recently proposed Adversarial-neural Topic Model models topics with an adversarially trained generator network and employs Dirichlet prior to capture the semantic patterns in latent topics.
arxiv  

On‐treatment dynamics of circulating extracellular vesicles in the first‐line setting of patients with advanced non‐small cell lung cancer: the LEXOVE prospective study

open access: yesMolecular Oncology, EarlyView.
The LEXOVE prospective study evaluated plasma cell‐free extracellular vesicle (cfEV) dynamics using Bradford assay and dynamic light scattering in metastatic non‐small cell lung cancer patients undergoing first‐line treatments, correlating a ∆cfEV < 20% with improved median progression‐free survival in responders versus non‐responders.
Valerio Gristina   +17 more
wiley   +1 more source

Topics in volatility models

open access: yes, 2009
In this thesis I will present my PhD research work, focusing mainly on financial modelling of asset’s volatility and the pricing of contingent claims (financial derivatives), which consists of four topics: 1. Several changing volatility models are introduced and the pricing of European options is derived under these models; 2.
Yi, Cong, Yi, Cong
openaire   +4 more sources

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

open access: yesMolecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić   +31 more
wiley   +1 more source

An Automatic Approach for Document-level Topic Model Evaluation [PDF]

open access: yesarXiv, 2017
Topic models jointly learn topics and document-level topic distribution. Extrinsic evaluation of topic models tends to focus exclusively on topic-level evaluation, e.g. by assessing the coherence of topics. We demonstrate that there can be large discrepancies between topic- and document-level model quality, and that basing model evaluation on topic ...
arxiv  

Labeled Interactive Topic Models [PDF]

open access: yesarXiv, 2023
Topic models are valuable for understanding extensive document collections, but they don't always identify the most relevant topics. Classical probabilistic and anchor-based topic models offer interactive versions that allow users to guide the models towards more pertinent topics.
arxiv  

Targeting rapid TKI‐induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale   +9 more
wiley   +1 more source

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