Results 31 to 40 of about 642,884 (313)

Topical Nano and Microemulsions for Skin Delivery

Pharmaceutics, 2017
Nanosystems such as microemulsions (ME) and nanoemulsions (NE) offer considerable opportunities for targeted drug delivery to and via the skin. ME and NE are stable colloidal systems composed of oil and water, stabilised by a mixture of surfactants and ...
Christofori M. R. R. Nastiti, T. Ponto, E. Abd, J. Grice, H. Benson, M. Roberts   +5 more
semanticscholar   +1 more source

Topical tofacitinib for atopic dermatitis: a phase IIa randomized trial

British Journal of Dermatology, 2016
Despite unmet need, 15 years have passed since a topical therapy with a new mechanism of action for atopic dermatitis (AD) has been approved. Janus kinase (JAK) inhibitor treatment effect via topical application in patients with AD is unknown.
R. Bissonnette, K. Papp, Y. Poulin, M. Gooderham, M. Raman, L. Mallbris, Cunshan Wang, V. Purohit, C. Mamolo, Jocelyne Papacharalambous, W. Ports   +10 more
semanticscholar   +1 more source

Relative efficacy and safety of topical non-steroidal anti-inflammatory drugs for osteoarthritis: a systematic review and network meta-analysis of randomised controlled trials and observational studies

British Journal of Sports Medicine, 2018
Objectives To compare the efficacy and safety of topical non-steroidal anti-inflammatory drugs (NSAIDs), including salicylate, for the treatment of osteoarthritis (OA).
C. Zeng, Jie Wei, M. Persson, A. Sarmanova, M. Doherty, D. Xie, Yilun Wang, Xiao-xiao Li, Jiatian Li, H. Long, G. Lei, Weiya Zhang   +11 more
semanticscholar   +1 more source

Application of sebomics for the analysis of residual skin surface components to detect potential biomarkers of type-1 diabetes mellitus

Scientific Reports, 2017
Metabolic imbalance in chronic diseases such as type-1 diabetes may lead to detectable perturbations in the molecular composition of residual skin surface components (RSSC).
Satyajit S. Shetage, Matthew J. Traynor, Marc B. Brown, Thomas M. Galliford, Robert P. Chilcott   +4 more
doaj   +1 more source

Current and Emerging Topical Antibacterials and Antiseptics: Agents, Action, and Resistance Patterns

Clinical Microbiology Reviews, 2017
SUMMARY Bacterial skin infections represent some of the most common infectious diseases globally. Prevention and treatment of skin infections can involve application of a topical antimicrobial, which may be an antibiotic (such as mupirocin or fusidic ...
D. Williamson, G. Carter, B. Howden
semanticscholar   +1 more source

Transdermal and Topical Drug Administration in the Treatment of Pain

Molecules, 2018
The comprehensive treatment of pain is multidimodal, with pharmacotherapy playing a key role. An effective therapy for pain depends on the intensity and type of pain, the patients’ age, comorbidities, and appropriate choice of analgesic, its dose and ...
W. Leppert, M. Malec-Milewska, R. Zajączkowska, J. Wordliczek   +3 more
semanticscholar   +1 more source

Response of Cowpea (Vigna unguiculata L. Walp) Accessions to Moisture Stress

International Journal of Plant Biology
Cowpea is one of the most important leguminous crops in Sub-Saharan Africa (SSA), and moisture stress is among the constraints affecting its productivity. This study was conducted to understand the response of cowpea accessions to moisture stress.
Nyimasata Manneh, Victor O. Adetimirin, Ibnou Dieng, Solomon O. Ntukidem, Christian A. Fatokun, Ousmane Boukar   +5 more
doaj   +1 more source

Autophagy in cancer and protein conformational disorders

FEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Editorial: Aerosol Research – a new diamond open-access journal covering the breadth of aerosol science and technology [PDF]

Aerosol Research, 2023
J. Elm, J. Elm, J. Elm, A. Czitrovszky, A. Czitrovszky, A. Held, A. Held, A. Virtanen, A. Virtanen, A. Kiendler-Scharr, B. J. Murray, B. J. Murray, B. J. Murray, D. McCluskey, D. McCluskey, D. Contini, D. Contini, D. Broday, D. Broday, E. Goudeli, E. Goudeli, E. Goudeli, H. Timonen, H. Timonen, J. Rosell-Llompart, J. Rosell-Llompart, J. Rosell-Llompart, J. L. Castillo, J. L. Castillo, E. Diapouli, E. Diapouli, M. Viana, M. Viana, M. E. Messing, M. E. Messing, M. Kulmala, M. Kulmala, N. Zíková, N. Zíková, S. H. Schmitt, S. H. Schmitt   +40 more
doaj   +1 more source

Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies

Molecular Oncology, EarlyView.
Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren, Philippe Decruyenaere, Francisco Avila Cobos, Johanna Bult, Jill Deleu, Laudonia Lidia Dipalo, Hetty Hilde Helsmoortel, Eva Hulstaert, Annelien Morlion, Elena Ramos Varas, Kathleen Schoofs, Wim Trypsteen, Eveline Vanden Eynde, Hanne Van Droogenbroeck, Kimberly Verniers, Jo Vandesompele, Anneleen Decock   +16 more
wiley   +1 more source