Results 41 to 50 of about 658,981 (342)

Current and Emerging Topical Antibacterials and Antiseptics: Agents, Action, and Resistance Patterns

Clinical Microbiology Reviews, 2017
SUMMARY Bacterial skin infections represent some of the most common infectious diseases globally. Prevention and treatment of skin infections can involve application of a topical antimicrobial, which may be an antibiotic (such as mupirocin or fusidic ...
D. Williamson, G. Carter, B. Howden
semanticscholar   +1 more source

On Topics Today [PDF]

Zeitschrift der Gesellschaft für Musiktheorie [Journal of the German-Speaking Society of Music Theory], 2007
This article surveys the state of so-called topic theory today. It charts its development through two generations of topic theorists. The first is constructed around three influential texts: Leonard Ratners seminal book that established the discipline in its own right, Classic music: expression, form and style (1980); Wye Allanbrooks.
openaire   +4 more sources

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

FEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur, Brian Acquaviva, Baylee A. Smith, Nathan Walker, Isabella Walter, Matthew L. Wohlever   +5 more
wiley   +1 more source

Editorial: Aerosol Research – a new diamond open-access journal covering the breadth of aerosol science and technology [PDF]

Aerosol Research, 2023
J. Elm, J. Elm, J. Elm, A. Czitrovszky, A. Czitrovszky, A. Held, A. Held, A. Virtanen, A. Virtanen, A. Kiendler-Scharr, B. J. Murray, B. J. Murray, B. J. Murray, D. McCluskey, D. McCluskey, D. Contini, D. Contini, D. Broday, D. Broday, E. Goudeli, E. Goudeli, E. Goudeli, H. Timonen, H. Timonen, J. Rosell-Llompart, J. Rosell-Llompart, J. Rosell-Llompart, J. L. Castillo, J. L. Castillo, E. Diapouli, E. Diapouli, M. Viana, M. Viana, M. E. Messing, M. E. Messing, M. Kulmala, M. Kulmala, N. Zíková, N. Zíková, S. H. Schmitt, S. H. Schmitt   +40 more
doaj   +1 more source

Does Intra-Wound Vancomycin Powder Affect the Action of Intra-Articular Tranexamic Acid in Total Joint Replacement?

Microorganisms, 2020
The intra-articular use of tranexamic acid (TXA) has contributed to reduced blood loss in total joint arthroplasty (TJA). The purpose of this study is to assess the efficacy of simultaneously topical use of tranexamic acid and vancomycin powder within ...
Antonios A. Koutalos, Athanasios Drakos, Apostolos Fyllos, Nikos Doxariotis, Sokratis Varitimidis, Konstantinos N. Malizos   +5 more
doaj   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

Transdermal and Topical Drug Administration in the Treatment of Pain

Molecules, 2018
The comprehensive treatment of pain is multidimodal, with pharmacotherapy playing a key role. An effective therapy for pain depends on the intensity and type of pain, the patients’ age, comorbidities, and appropriate choice of analgesic, its dose and ...
W. Leppert, M. Malec-Milewska, R. Zajączkowska, J. Wordliczek   +3 more
semanticscholar   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Topical ferumoxytol nanoparticles disrupt biofilms and prevent tooth decay in vivo via intrinsic catalytic activity

Nature Communications, 2018
Ferumoxytol is a nanoparticle formulation approved by the U.S. Food and Drug Administration for systemic use to treat iron deficiency. Here, we show that, in addition, ferumoxytol disrupts intractable oral biofilms and prevents tooth decay (dental caries)
Yuan Liu, P. Naha, G. Hwang, Dongyeop Kim, Yue Huang, Aurea Simón-Soro, H. Jung, Z. Ren, Yong Li, S. Gubara, F. Alawi, D. Zero, A. Hara, D. Cormode, H. Koo   +14 more
semanticscholar   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source