Results 51 to 60 of about 651,073 (343)

Sodium Hypochlorite 0.005% Versus Placebo in the Treatment of Mild to Moderate Acne: A Double-Blind Randomized Controlled Trial

Dermatology Practical & Conceptual, 2021
Background: Acne vulgaris is a common inflammatory disease of the pilosebaceous follicle that affects many teenagers and young people. There is an obvious need for topical treatments with good tolerability and efficacy for the management of acne lesions.
Azadeh Dorostkar, Mehdi Ghahartars, Mohammad Reza Namazi, Nafiseh Todarbary, Maryam Hadibarhaghtalab, Maryam Rezaee   +5 more
doaj   +1 more source

Co‐overexpression of the caloric restriction‐induced mitochondrial factors PGC‐1α and MIPEP upregulates Phospho1 expression in adipocytes

FEBS Open Bio, EarlyView.
Caloric restriction that extends lifespan induces the expression of PGC‐1α and MIPEP in white adipose tissue. In this study, co‐overexpression of Pgc‐1α and Mipep upregulated the gene expression of PHOSPHO1. These findings provide new insights into mitochondria‐related mechanisms underlying the effects of caloric restriction in adipocytes.
Mamiko Ishimatsu, Kanari Taki, Asuka Hayami, Komachi Kato, Yuka Nozaki, Yuhei Mizunoe, Takumi Narita, Ryoichi Mori, Yoshikazu Higami, Masaki Kobayashi   +9 more
wiley   +1 more source

Topical Word Embeddings

AAAI Conference on Artificial Intelligence, 2015
Most word embedding models typically represent each word using a single vector, which makes these models indiscriminative for ubiquitous homonymy and polysemy. In order to enhance discriminativeness, we employ latent topic models to assign topics for
Y. Liu, Zhiyuan Liu, Tat-Seng Chua, Maosong Sun   +3 more
semanticscholar   +1 more source

CD9‐association with PIP2 areas is regulated by a CD9 salt bridge

FEBS Open Bio, EarlyView.
The tetraspanin CD9 has an intracellular salt bridge. If CD9 opens, open‐CD9 moves from PIP2‐rich areas to regions populated by its interaction partner EWI‐2. Hence, the state of the salt bridge regulates the distribution of CD9 and by this CD9‐EWI‐2 complex formation.
Yahya Homsi, Sara C. Konopka, Thorsten Lang   +2 more
wiley   +1 more source

Interventions in cytokine signaling: novel horizons for psoriasis treatment

Frontiers in Immunology
Intricate interactions between immune cells and cytokines define psoriasis, a chronic inflammatory skin condition that is immunological-mediated. Cytokines, including interleukins (ILs), interferons (IFNs), tumor necrosis factors (TNFs), chemokines, and ...
Lisha Li, Lisha Li, Lisha Li, Jun Liu, Jun Liu, Jiaye Lu, Jiaye Lu, Junchao Wu, Junchao Wu, Xinyue Zhang, Xinyue Zhang, Tianyou Ma, Tianyou Ma, Xiying Wu, Xiying Wu, Quangang Zhu, Quangang Zhu, Zhongjian Chen, Zhongjian Chen, Zongguang Tai, Zongguang Tai   +20 more
doaj   +1 more source

Polydatin ameliorates ovalbumin‐induced asthma in a rat model through NCOA4‐mediated ferroautophagy and ferroptosis pathway

FEBS Open Bio, EarlyView.
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li, Yuwei Tang, Wenkang Liu, Fang Fang, Jiepeng Wang, Chaoyi Fang   +5 more
wiley   +1 more source

An Overview of Tissue Engineering as an Alternative for Toxicity Assessment

Journal of Pharmacy & Pharmaceutical Sciences, 2016
Tissue engineering is a multidisciplinary field that combines aspects of biology, material sciences, engineering and medicine - the ultimate goal being able to fabricate replacement tissues and/or organs for an ageing population.
Mathew Garrod, David Yi San Chau
doaj   +1 more source

Teaching Python with team‐based learning: using cloud‐based notebooks for interactive coding education

FEBS Open Bio, EarlyView.
This study presents a novel approach to teaching Python and bioinformatics using team‐based learning and cloud‐hosted notebooks. By integrating interactive coding into biomedical education, the method improves accessibility, student engagement, and confidence—especially for those without a computing background.
Nuno S. Osório, Leonardo D. Garma
wiley   +1 more source

Most autophagic cell death studies lack evidence of causality

FEBS Open Bio, EarlyView.
Of 104 studies claiming autophagic cell death (ACD), only 13 demonstrated both causality and exclusion of apoptosis to confirm true ACD. Most studies relied on correlation‐level data or measured autophagy in isolation, revealing pervasive methodological shortcomings.
Ali Burak Özkaya, Yasmin Ghaseminejad
wiley   +1 more source

Topics in Cosmology [PDF]

Proceedings of School on Particle Physics, Gravity and Cosmology — PoS(P2GC), 2007
Invited lectures at the Summer School on Particle Physics, Gravity and Cosmology (Dubrovnik, August 2006), publ. in the on-line proceedings (PoS(P2GC)007).
openaire   +3 more sources