Results 1 to 10 of about 325,333 (335)

Delivery of biologics: Topical administration. [PDF]

Biomaterials, 2023
Biologics are unaffordable to a large majority of the global population because of prohibitively expensive fermentation systems, purification and the requirement for cold chain for storage and transportation. Limitations of current production and delivery systems of biologics were evident during the recent pandemic when 90% are delivered using invasive
Kulchar RJ, Singh R, Ding S, Alexander E, Leong KW, Daniell H.   +5 more
europepmc   +5 more sources

Protective Effects of Topical Administration of Laminarin in Oxazolone-Induced Atopic Dermatitis-like Skin Lesions [PDF]

Marine Drugs, 2022
Laminarin is a polysaccharide isolated from brown marine algae and has a wide range of bioactivities, including immunoregulatory and anti-inflammatory properties. However, the effects of laminarin on atopic dermatitis have not been demonstrated.
Tae-Kyeong Lee, Dae Won Kim, Ji Hyeon Ahn, Choong-Hyun Lee, Jae-Chul Lee, Soon Sung Lim, Il Jun Kang, Seongkweon Hong, Soo Young Choi, Moo-Ho Won, Joon Ha Park   +10 more
doaj   +2 more sources

Silk peptide-hyaluronic acid based nanogels for the enhancement of the topical administration of curcumin [PDF]

Frontiers in Chemistry, 2022
The present study focused on the development of Cur-loaded SOHA nanogels (Cur-SHNGs) to enhance the topical administration of Cur. The physiochemical properties of Cur-SHNGs were characterized.
Jiangxiu Niu, Ming Yuan, Yao Liu, Liye Wang, Zigui Tang, Yihan Wang, Yueheng Qi, Yansong Zhang, Huiyuan Ya, Yanli Fan   +9 more
doaj   +2 more sources

Dendrimer and dendrimer gel-derived drug delivery systems: Breaking bottlenecks of topical administration of glaucoma medications. [PDF]

MedComm Biomater Appl, 2023
Wang J, Li B, Kompella UB, Yang H.
europepmc   +3 more sources

Acute Hyperglycemia Due to Topical Corticosteroid Administration

Case Reports in Endocrinology, 2019
We present the case of a 71-year-old man with longstanding, previously well-controlled type 1 diabetes who developed acute hyperglycemia. His insulin requirements, via his insulin pump, increased to nearly five times his typical daily dose.
Laura Y. Sue, Anna Milanesi
doaj   +5 more sources

Contribution of CARD9 signaling to wound healing in skin promoted by topical administration of heat-killed <i>Enterococcus faecalis</i> strain KH2 and the involvement of Dectin-2. [PDF]

Front Immunol
Kurosaka S, Tanno H, Hirose M, Kamada W, Takayashiki R, Sone I, Sato Y, Watanabe T, Ishi S, Shoji M, Imai Y, Sato K, Ishii K, Hara H, Yamasaki S, Saijo S, Iwakura Y, Kawakami K, Kanno E.   +18 more
europepmc   +3 more sources

Topical Administration of an Apoptosis Inducer Mitigates Bleomycin-Induced Skin Fibrosis. [PDF]

ACS Pharmacol Transl Sci, 2023
Huda MN, Borrego EA, Guerena CD, Varela-Ramirez A, Aguilera RJ, Hamadani CM, Tanner EEL, Badruddoza AZM, Agarwal SK, Nurunnabi M.   +9 more
europepmc   +3 more sources

Graphene Oxide Topical Administration: Skin Permeability Studies [PDF]

Materials, 2021
Nanostructured carriers have been widely used in pharmaceutical formulations for dermatological treatment. They offer targeted drug delivery, sustained release, improved biostability, and low toxicity, usually presenting advantages over conventional formulations. Due to its large surface area, small size and photothermal properties, graphene oxide (GO)
Filipa A. L. S. Silva, Raquel Costa-Almeida, Licínia Timochenco, Sara I. Amaral, Soraia Pinto, Inês C. Gonçalves, José R. Fernandes, Fernão D. Magalhães, Bruno Sarmento, Artur M. Pinto   +9 more
openaire   +3 more sources

Cryoanesthesia with ethyl chloride spray versus 5% lidocaine gel in alleviating oral local anesthetic injection pain for buccal anaesthesia: A randomized clinical (controlled) trial [PDF]

Journal of Dental Research, Dental Clinics, Dental Prospects, 2023
Background. Numbing the area of oral mucosa with cold application prior to administration of regional anesthesia has been widely used by various dentists in alleviating pain caused by needle prick.
Hira Abbasi, Faiza Ali, Hina Aslam, Muhammad Sharjeel Khan, Muhammad Waqas, Abhishek Lal   +5 more
doaj   +1 more source

A Review on the Role of Pilocarpine on the Management of Xerostomia and the Importance of the Topical Administration Systems Development

Pharmaceuticals, 2022
Xerostomia is linked to an increased risk of dental caries, oral fungal infections, and speaking/swallowing difficulties, factors that may significantly degrade patients’ life, socially- or emotionally-wise.
Afroditi Kapourani, Konstantinos N. Kontogiannopoulos, Panagiotis Barmpalexis   +2 more
doaj   +1 more source