Results 1 to 10 of about 2,655,093 (273)
Delivery of biologics: Topical administration. [PDF]
Biomaterials, 2023 Biologics are unaffordable to a large majority of the global population because of prohibitively expensive fermentation systems, purification and the requirement for cold chain for storage and transportation. Limitations of current production and delivery systems of biologics were evident during the recent pandemic when 90% are delivered using invasive
R. Kulchar +5 more
semanticscholar +6 more sources
Protective Effects of Topical Administration of Laminarin in Oxazolone-Induced Atopic Dermatitis-like Skin Lesions [PDF]
Marine Drugs, 2022 Laminarin is a polysaccharide isolated from brown marine algae and has a wide range of bioactivities, including immunoregulatory and anti-inflammatory properties. However, the effects of laminarin on atopic dermatitis have not been demonstrated.
Tae-Kyeong Lee +10 more
doaj +3 more sources
Pharmaceuticals, 2022 Xerostomia is linked to an increased risk of dental caries, oral fungal infections, and speaking/swallowing difficulties, factors that may significantly degrade patients’ life, socially- or emotionally-wise.
Afroditi Kapourani +2 more
doaj +2 more sources
Nanostructured Lipid Carriers Enriched Hydrogels for Skin Topical Administration of Quercetin and Omega-3 Fatty Acid [PDF]
Pharmaceutics, 2023 Chronic skin exposure to external hostile agents (e.g., UV radiation, microorganisms, and oxidizing chemicals) may increase oxidative stress, causing skin damage and aging.
M. Lúcio +11 more
semanticscholar +2 more sources
Systemic and topical administration of spermidine accelerates skin wound healing
Cell Communication and Signaling, 2021 Background The skin wound healing process is regulated by various cytokines, chemokines, and growth factors. Recent reports have demonstrated that spermine/spermidine (SPD) promote wound healing through urokinase-type plasminogen activator (uPA)/uPA ...
Daisuke Ito +5 more
doaj +2 more sources
Topical Administration of Mometasone Is Not Helpful in Post-COVID-19 Olfactory Dysfunction [PDF]
Life (Basel), 2022 Persistent olfactory dysfunction is a major concern post-COVID-19, affecting up to 5% of all patients. Different therapeutic options, including mometasone nasal spray, have been recommended, only some of which have been validated for post-COVID-19 ...
C. Hintschich +3 more
semanticscholar +2 more sources
Topical administration of Juglans regia L. leaf extract accelerates diabetic wound healing [PDF]
BMC Complement Med Ther, 2022 Background Diabetic wounds are one of the most important issues in diabetic patients. It seems that Juglans regia L. leaf with antioxidant and anti-inflammatory potentials can be profitable for healing of diabetic wounds.
Davood Nasiry +4 more
semanticscholar +2 more sources
BJS Open, 2019 Background Topical administration of tranexamic acid (TXA) reduces bleeding from surgical wounds similarly to intravenous use, but with negligible risk of adverse systemic events. Topical use is expanding, but is off‐label.
T. A. Eikebrokk +5 more
doaj +2 more sources
Silk peptide-hyaluronic acid based nanogels for the enhancement of the topical administration of curcumin [PDF]
Frontiers in Chemistry, 2022 The present study focused on the development of Cur-loaded SOHA nanogels (Cur-SHNGs) to enhance the topical administration of Cur. The physiochemical properties of Cur-SHNGs were characterized.
Jiangxiu Niu +9 more
doaj +2 more sources
Acute Hyperglycemia Due to Topical Corticosteroid Administration
Case Reports in Endocrinology, 2019 We present the case of a 71-year-old man with longstanding, previously well-controlled type 1 diabetes who developed acute hyperglycemia. His insulin requirements, via his insulin pump, increased to nearly five times his typical daily dose.
Laura Y. Sue, Anna Milanesi
doaj +5 more sources