Results 91 to 100 of about 2,618,736 (325)

Dexamethasone distribution characteristic following controllable continuous sub-tenon drug delivery in rabbit

Drug Delivery, 2017
Drug delivery systems are required to be safe, minimally invasive and effectively delivery drug to the target tissues. But delivery drugs to the eye has not yet satisfied this need. Here, we focused on examining the distribution of dexamethasone (DEX) in
Xuetao Huang, Manqiang Peng, Yezhen Yang, Yiqin Duan, Kuanshu Li, Shaogang Liu, Changhua Ye, Ding Lin   +7 more
doaj   +1 more source

Topical Remedies for the Treatment of Men’s Sexual Dysfunction from the Perspective of Traditional Persian Medicine: A Review Article [PDF]

Journal of Health Sciences and Surveillance System
Background: Sexual dysfunction is one of the most prevalent complaints in men over 50 years old, which can negatively affect marital life and self-esteem.
Abdolreza Haghpanah, Amir Mohammad Jaladat, Fatemeh Atarzadeh, Amirhossein Hassani, Elham Akbarzadeh, Mohammad Mahdi Parvizi   +5 more
doaj   +1 more source

Latanoprost with high precision, piezo-print microdose delivery for IOP lowering: clinical results of the PG21 study of 0.4 µg daily microdose. [PDF]

, 2018
Background:Topical high-precision piezo-print delivery of microdoses of latanoprost achieved significant IOP reduction consistent with the eyedropper effect but with a 75% reduced exposure to drugs and preservatives.
Ianchulev, Tsontcho, Kramm, Robert L, Lin, Shan, Pasquale, Louis R, Tsai, James C, Weinreb, Robert N   +5 more
core  

Diagnosis and Treatment of Infectious Enteritis in Adult Ruminants. [PDF]

, 2018
Infectious enteritis in adult ruminants is often a result of 1 or more viral, bacterial, or parasitic pathogens. Diagnosis of etiologic agents causing enteritis is important when considering herd implications and zoonotic potential of some etiologies ...
Chigerwe, Munashe, Heller, Meera C
core   +1 more source

Characteristics of Cerebral Palsy in the Midwestern US

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebral palsy (CP) is the most common lifelong motor disability worldwide. Yet, data is limited on how CP manifests in the US. Our objective was to characterize and determine factors affecting functional outcomes in a large population of young people with CP in the Midwestern US.
Susie Kim, Kelsey Steffen, Lauren Gottschalk‐Henneberry, Jennifer Miros, Amy Robichaux‐Viehoever, Karen Taca, Bhooma R. Aravamuthan   +6 more
wiley   +1 more source

Exploratory study on the efficacy of topical pan-JAK inhibitor in ocular and skin GVHD in a sclerodermatous GVHD mouse model

Scientific Reports
Systemic administration of Janus kinase (JAK) inhibitors is effective in treating chronic graft-versus-host disease (cGVHD) but is associated with side effects. Topical drug administration effectively minimizes side effects.
Shinri Sato, Yoko Ogawa, Kazuki Asai, Eisuke Shimizu, Shota Shimizu, Hiroko Taniguchi, Takahiro Okazaki, Shigeto Shimmura, Kazuno Negishi, Masatoshi Hirayama   +9 more
doaj   +1 more source

Preparation and Evaluation of Glutathione Semisolid Formulation as a Candidate for Anti-wrinkle and Skin-Lightening [PDF]

مجله علوم پزشکی صدرا
Introduction: In recent years, there has been a growth in the demand for skincare services and products. In this study, a topical formulation composed of glutathione loaded into niosomes was developed, and its physical, chemical, and microbial ...
Mohammad-Mehdi Khazaei, Negin Mozafari, Soliman Mohammadi-Samani, Hajar Ashrafi, Amir Azadi   +4 more
doaj   +1 more source

Improved Biosafety and Transdermal Delivery of Aconitine via Diethylene Glycol Monoethyl Ether-Mediated Microemulsion Assisted with Microneedles

Pharmaceutics, 2020
In the current study, diethylene glycol monoethyl ether-mediated microemulsions were combined with microneedles for enhanced transdermal aconitine delivery.
Yongtai Zhang, Hongmei Hu, Qian Jing, Zhi Wang, Zehui He, Tong Wu, Nian-Ping Feng   +6 more
doaj   +1 more source

NGX-4010, a capsaicin 8% patch, for the treatment of painful HIV-associated distal sensory polyneuropathy: integrated analysis of two phase III, randomized, controlled trials [PDF]

, 2013
BACKGROUND HIV-associated distal sensory polyneuropathy (HIV-DSP) is the most frequently reported neurologic complication associated with HIV infection.
Brew, Bruce J, Brown, Stephen, Fisher, Martin, Larbalestier, Nicholas, Moyle, Graeme, Orkin, Chloe, Schifitto, Giovanni, Simpson, David M, Tobias, Jeffrey K, Vanhove, Geertrui F   +9 more
core   +1 more source

Economic Burden of Rheumatoid Arthritis in Low‐ and Middle‐Income Countries: Systematic Review and Meta‐Analysis

Arthritis Care &Research, EarlyView.
Objective The aim of this systematic review was to synthesize the economic impact of rheumatoid arthritis (RA) on households, health systems, and society in low‐ and middle‐income countries (LMICs). Methods Electronic databases such as PubMed, Web of Science, and CINAHL were searched using keywords related to RA and cost of illness.
Tadesse Gebrye, Chidozie E. Mbada, Clara T. Fatoye, Faatihah Niyi‐Odumosu, Ushotanefe Useh, Zalmai Hakimi, Francis Fatoye   +6 more
wiley   +1 more source