Results 21 to 30 of about 2,655,093 (273)

Topical ocular delivery of nanoparticles with epoetin beta in Wistar Hannover rats

open access: yesScientific Reports, 2023
Topical instillation of drugs targeting the posterior ocular segment is an expanding area of research. Chitosan and hyaluronic acid have remarkable mucoadhesive properties and potentially enhance pre-corneal retention time after topical instillation ...
Beatriz Silva   +3 more
doaj   +1 more source

Norcantharidin Nanoemulsion Development, Characterization, and In Vitro Antiproliferation Effect on B16F1 Melanoma Cells

open access: yesPharmaceuticals, 2023
Melanoma is a highly lethal type of cancer that has had an increase in incidence in the last decades. Nevertheless, current therapies lack effectiveness and have highly disabling side effects, which calls for new therapeutic strategies.
Gabriel Martínez-Razo   +5 more
doaj   +1 more source

Topical ophthalmic atropine in horses, pharmacokinetics and effect on intestinal motility

open access: yesBMC Veterinary Research, 2021
Background Topical ophthalmic atropine sulfate is an important part of the treatment protocol in equine uveitis. Frequent administration of topical atropine may cause decreased intestinal motility and colic in horses due to systemic exposure.
L. Ström   +7 more
doaj   +1 more source

Antibacterial Effect of Topically Administered Tranexamic Acid in Large Joint Arthroplasty

open access: yesApplied Sciences, 2023
Tranexamic acid (TXA) is a synthetic derivative of the amino acid lysine and is commonly used as an antifibrinolytic agent in large joint surgery, such as knee arthroplasty, to minimize blood loss and its associated complications.
Urban Slokar   +3 more
doaj   +1 more source

TOPICAL NONSTEROID ANTI-INFLAMATORY DRUGS – INDICATIONS, EFFICACY AND SAFETY [PDF]

open access: yesRomanian Journal of Rheumatology, 2019
Topical Nonsteroid anti-inflammatory drugs are efficient for the treatment of acute and chronic pain in musculo-skeletal diseases. There clinical benefit is similar to the oral form of administration, but with significant less systemic adverse events ...
Diana Mazilu, Ruxandra Ionescu
doaj   +1 more source

Study of bases influence on the biopharmaceutical characteristics of the pastes for onychomycosis therapy

open access: yesAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2018
According to the European and American authors the onychomycosis prevalence in the world has amount from 8.0 % to 26.9 %. Topical treatment of onychomycosis in most cases is the only acceptable method of therapy mainly due to high safety.
V. V. Luc   +3 more
doaj   +1 more source

Topical Administration of Cannabidiol: Influence of Vehicle-Related Aspects on Skin Permeation Process

open access: yesPharmaceuticals, 2020
Cannabidiol (CBD) is a non-psychoactive cannabinoid isolated from Cannabis sativa which, given its claimed beneficial properties and therapeutic potential, has lately aroused considerable attention from the scientific community.
A. Casiraghi   +4 more
semanticscholar   +1 more source

3-hydroxykynurenine suppresses CD4+ T-cell proliferation, induces T-regulatory-cell development, and prolongs corneal allograft survival [PDF]

open access: yes, 2011
Copyright © 2011 Association for Research in Vision and Ophthalmology. This article is available open access through the publisher’s website at the link below.Purpose.
Fu, Hongmei   +4 more
core   +2 more sources

Bisphosphonate: Brief Review of Its Development for Usage in Dentistry

open access: yesJournal of Dentistry Indonesia, 2013
Bisphosphonate (BP) is a class of drug that prevent the loss of bone mass. It inhibits the resorption of bone by encouraging osteoclast to undergo apoptosis.
Tita Ratya Utari
doaj   +1 more source

Gelatin Nanoparticles-HPMC Hybrid System for Effective Ocular Topical Administration of Antihypertensive Agents

open access: yesPharmaceutics, 2020
The increment in ocular drug bioavailability after topical administration is one of the main challenges in pharmaceutical technology. For several years, different strategies based on nanotechnology, hydrogels or implants have been evaluated.
Sergio Esteban-Pérez   +5 more
semanticscholar   +1 more source

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