Results 21 to 30 of about 326,407 (374)

Topical ocular delivery of nanoparticles with epoetin beta in Wistar Hannover rats

open access: yesScientific Reports, 2023
Topical instillation of drugs targeting the posterior ocular segment is an expanding area of research. Chitosan and hyaluronic acid have remarkable mucoadhesive properties and potentially enhance pre-corneal retention time after topical instillation ...
Beatriz Silva   +3 more
doaj   +1 more source

In Vivo Evaluation of Cefuroxime Axetil-Loaded Bioadhesive Nanoparticles to Treat Haemophilus influenzae-Induced Otitis Media

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
Otitis media (OM) is a common disease in children. One of the most common pathogens causing OM is non-typeable Haemophilus influenzae (NTHi). NTHi in the middle ear can be successfully eradicated by a regimen of oral antibiotics sustained for 7–10 days ...
Hong Lin   +6 more
doaj   +1 more source

Topical ophthalmic atropine in horses, pharmacokinetics and effect on intestinal motility

open access: yesBMC Veterinary Research, 2021
Background Topical ophthalmic atropine sulfate is an important part of the treatment protocol in equine uveitis. Frequent administration of topical atropine may cause decreased intestinal motility and colic in horses due to systemic exposure.
L. Ström   +7 more
doaj   +1 more source

TOPICAL NONSTEROID ANTI-INFLAMATORY DRUGS – INDICATIONS, EFFICACY AND SAFETY [PDF]

open access: yesRomanian Journal of Rheumatology, 2019
Topical Nonsteroid anti-inflammatory drugs are efficient for the treatment of acute and chronic pain in musculo-skeletal diseases. There clinical benefit is similar to the oral form of administration, but with significant less systemic adverse events ...
Diana Mazilu, Ruxandra Ionescu
doaj   +1 more source

Antibacterial Effect of Topically Administered Tranexamic Acid in Large Joint Arthroplasty

open access: yesApplied Sciences, 2023
Tranexamic acid (TXA) is a synthetic derivative of the amino acid lysine and is commonly used as an antifibrinolytic agent in large joint surgery, such as knee arthroplasty, to minimize blood loss and its associated complications.
Urban Slokar   +3 more
doaj   +1 more source

Effects of Eye Drops Containing Hyaluronic Acid-Nimesulide Conjugates in a Benzalkonium Chloride-Induced Experimental Dry Eye Rabbit Model

open access: yesPharmaceutics, 2021
Dry eye syndrome (DES) is a common ocular disease worldwide. Currently, anti-inflammatory agents and immunosuppressive drugs, such as cyclosporine A, have been widely used to treat this chronic condition. However, the multifactorial etiology of DES, poor
Tzu-Yang Chen   +5 more
doaj   +1 more source

3-hydroxykynurenine suppresses CD4+ T-cell proliferation, induces T-regulatory-cell development, and prolongs corneal allograft survival [PDF]

open access: yes, 2011
Copyright © 2011 Association for Research in Vision and Ophthalmology. This article is available open access through the publisher’s website at the link below.Purpose.
Fu, Hongmei   +4 more
core   +2 more sources

Effects of Combined Intralesional 5-Fluorouracil and Topical Silicone in Prevention of Keloids: A Double Blind Randomized Clinical Trial Study [PDF]

open access: yesActa Medica Iranica, 2011
Keloids are aesthetically disfiguring and severely disabling. The optimal treatment remains undefined. This clinical study, evaluate the efficacy and side effects of combined topical silicone and 5-Fluorouracil on the prevention of keloids.
Ebrahim Hatamipour   +3 more
doaj   +1 more source

Norcantharidin Nanoemulsion Development, Characterization, and In Vitro Antiproliferation Effect on B16F1 Melanoma Cells

open access: yesPharmaceuticals, 2023
Melanoma is a highly lethal type of cancer that has had an increase in incidence in the last decades. Nevertheless, current therapies lack effectiveness and have highly disabling side effects, which calls for new therapeutic strategies.
Gabriel Martínez-Razo   +5 more
doaj   +1 more source

Ropivacaine vs tetracaine in topical anesthesia for intravitreal injection [PDF]

open access: yes, 2015
Aim: The object of the study was to evaluate the long term efficacy and safety of ropivacaine 0,5% vs tetracaine 0,5% for topical anesthesia in intravitreal injection of dexamethasone in patients with diabetic macular edema (DME) and anti-vascular ...
COLLINI, Saul   +6 more
core   +1 more source

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