Results 31 to 40 of about 217,333 (230)

Polymeric Biomaterials for Topical Drug Delivery in the Oral Cavity: Advances on Devices and Manufacturing Technologies

open access: yesPharmaceutics, 2022
There are several routes of drug administration, and each one has advantages and limitations. In the case of the topical application in the oral cavity, comprising the buccal, sublingual, palatal, and gingival regions, the advantage is that it is ...
Paula de Freitas Rosa Remiro   +5 more
doaj   +1 more source

Digital Divides and Online Media [PDF]

open access: yes, 2021
Digital divide has been a common concern during the past two or three decades; traditionally, it refers to a gap between developed and developing countries in the adoption and use of digital technologies. Given the importance of the topic, digital divide has been also extensively studied, although, hitherto, there is no previous research that would ...
arxiv   +1 more source

Effects of Eye Drops Containing Hyaluronic Acid-Nimesulide Conjugates in a Benzalkonium Chloride-Induced Experimental Dry Eye Rabbit Model

open access: yesPharmaceutics, 2021
Dry eye syndrome (DES) is a common ocular disease worldwide. Currently, anti-inflammatory agents and immunosuppressive drugs, such as cyclosporine A, have been widely used to treat this chronic condition. However, the multifactorial etiology of DES, poor
Tzu-Yang Chen   +5 more
doaj   +1 more source

Use of ozone-based eye drops. A series of cases in veterinary and human spontaneous ocular pathologies [PDF]

open access: yes, 2018
Conjunctivitis, keratoconjunctivitis, and corneal ulcers are common eye disorders frequently diagnosed in both humans and animals, and are currently treated by topical administration of eye drops containing anti-inflammatory and antibacterial agents. The
Marchegiani, Andrea   +3 more
core   +3 more sources

Norcantharidin Nanoemulsion Development, Characterization, and In Vitro Antiproliferation Effect on B16F1 Melanoma Cells

open access: yesPharmaceuticals, 2023
Melanoma is a highly lethal type of cancer that has had an increase in incidence in the last decades. Nevertheless, current therapies lack effectiveness and have highly disabling side effects, which calls for new therapeutic strategies.
Gabriel Martínez-Razo   +5 more
doaj   +1 more source

Antibacterial Effect of Topically Administered Tranexamic Acid in Large Joint Arthroplasty

open access: yesApplied Sciences, 2023
Tranexamic acid (TXA) is a synthetic derivative of the amino acid lysine and is commonly used as an antifibrinolytic agent in large joint surgery, such as knee arthroplasty, to minimize blood loss and its associated complications.
Urban Slokar   +3 more
doaj   +1 more source

Breaking down the Barrier: Topical Liposomes as Nanocarriers for Drug Delivery into the Posterior Segment of the Eyeball [PDF]

open access: yes, 2019
Topical instillation is the most widely preferred noninvasive route of drug administration to treat diseases affecting the anterior segment of the eye. Nonetheless, the ocular bioavailability for deeper ocular tissues is very low.
Altamirano-Vallejo, Juan C.   +4 more
core   +1 more source

Graphene Oxide Topical Administration: Skin Permeability Studies [PDF]

open access: yesMaterials, 2021
Nanostructured carriers have been widely used in pharmaceutical formulations for dermatological treatment. They offer targeted drug delivery, sustained release, improved biostability, and low toxicity, usually presenting advantages over conventional formulations. Due to its large surface area, small size and photothermal properties, graphene oxide (GO)
Filipa A. L. S. Silva   +9 more
openaire   +4 more sources

Ice versus lidocaine 5% gel for topical anaesthesia of oral mucosa – a randomized cross-over study

open access: yesBMC Anesthesiology, 2019
Background Topical anaesthesia is important to optimize pain control during dental injection. Our aim was to describe a new simple method for topical anaesthesia of oral mucosa and to compare the effectiveness of ice and lidocaine 5% gel for topical ...
Nishma Hindocha   +3 more
doaj   +1 more source

The combined use of oral and topical tranexamic acid is a safe, efficient and low-cost method in reducing blood loss and transfusion rates in total knee arthroplasty

open access: yesJournal of Orthopaedic Surgery, 2017
Aims: The combined (IV (intravenous) + topical) use of tranexamic acid (TXA) has been shown to be a safe method and more effective than single (IV or topical) application.
Deniz Cankaya   +5 more
doaj   +1 more source

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