Results 31 to 40 of about 2,598,787 (372)

Effect of Topical Administration of Somatostatin on Retinal Inflammation and Neurodegeneration in an Experimental Model of Diabetes

open access: yesJournal of Clinical Medicine, 2020
Somatostatin (SST) is a neuroprotective peptide but little is known regarding the potential role of its anti-inflammatory effects on retinal neuroprotection.
C. Hernández   +6 more
semanticscholar   +1 more source

Bisphosphonate: Brief Review of Its Development for Usage in Dentistry

open access: yesJournal of Dentistry Indonesia, 2013
Bisphosphonate (BP) is a class of drug that prevent the loss of bone mass. It inhibits the resorption of bone by encouraging osteoclast to undergo apoptosis.
Tita Ratya Utari
doaj   +1 more source

Topical Administration of SLN-Based Gene Therapy for the Treatment of Corneal Inflammation by De Novo IL-10 Production

open access: yesPharmaceutics, 2020
One of the main challenges in gene therapy is the issue of delivery, and it is especially relevant for the success of gene therapy in the cornea. In the present work, eye drops containing biocompatible non-viral vectors based on solid lipid nanoparticles
Mónica Vicente-Pascual   +7 more
semanticscholar   +1 more source

Corneal Infection Therapy with Topical Bacteriophage Administration [PDF]

open access: yesThe Open Ophthalmology Journal, 2015
Staphylococcus aureus is a major pathogen in bacterial keratitis, a vision-threatening disease. Although the incidence of S. aureus keratitis varies worldwide, the increasing trend of resistance to certain antibiotics makes this condition an important, global, healthcare concern.
Jean-Marc Legeais   +2 more
openaire   +3 more sources

Effects of Combined Intralesional 5-Fluorouracil and Topical Silicone in Prevention of Keloids: A Double Blind Randomized Clinical Trial Study [PDF]

open access: yesActa Medica Iranica, 2011
Keloids are aesthetically disfiguring and severely disabling. The optimal treatment remains undefined. This clinical study, evaluate the efficacy and side effects of combined topical silicone and 5-Fluorouracil on the prevention of keloids.
Ebrahim Hatamipour   +3 more
doaj   +1 more source

Norcantharidin Nanoemulsion Development, Characterization, and In Vitro Antiproliferation Effect on B16F1 Melanoma Cells

open access: yesPharmaceuticals, 2023
Melanoma is a highly lethal type of cancer that has had an increase in incidence in the last decades. Nevertheless, current therapies lack effectiveness and have highly disabling side effects, which calls for new therapeutic strategies.
Gabriel Martínez-Razo   +5 more
doaj   +1 more source

Steroid induced osteonecrosis: An analysis of steroid dosing risk. [PDF]

open access: yes, 2010
Osteonecrosis is a serious condition involving bone destruction that frequently requires surgical treatment to rebuild the joint. While there is an abundance of literature documenting corticosteroid related osteonecrosis, there is no consensus as to the ...
Chang, Christopher   +4 more
core   +1 more source

Tear Film Pharmacokinetics and Systemic Absorption Following Topical Administration of 1% Prednisolone Acetate Ophthalmic Suspension in Dogs

open access: yesFrontiers in Veterinary Science, 2020
The study aimed to determine the tear film pharmacokinetics following topical administration of 1% prednisolone acetate—assessing whether two drops would provide a superior kinetic profile compared to one drop—and to determine the fraction of an eye drop
L. Sebbag   +3 more
semanticscholar   +1 more source

Antibacterial Effect of Topically Administered Tranexamic Acid in Large Joint Arthroplasty

open access: yesApplied Sciences, 2023
Tranexamic acid (TXA) is a synthetic derivative of the amino acid lysine and is commonly used as an antifibrinolytic agent in large joint surgery, such as knee arthroplasty, to minimize blood loss and its associated complications.
Urban Slokar   +3 more
doaj   +1 more source

Ropivacaine vs tetracaine in topical anesthesia for intravitreal injection [PDF]

open access: yes, 2015
Aim: The object of the study was to evaluate the long term efficacy and safety of ropivacaine 0,5% vs tetracaine 0,5% for topical anesthesia in intravitreal injection of dexamethasone in patients with diabetic macular edema (DME) and anti-vascular ...
COLLINI, Saul   +6 more
core   +1 more source

Home - About - Disclaimer - Privacy