Results 31 to 40 of about 2,655,093 (273)

Comparison of topical and intravenous tranexamic acid for reducing postoperative blood loss in single-level posterior lumbar interbody fusion: a retrospective study from Japan [PDF]

open access: yesAsian Spine Journal
Study Design A retrospective cohort study. Purpose This study aimed to compare the efficacy and safety of topical and relatively high-dose intravenous tranexamic acid (TXA) in minimizing postoperative blood loss in patients undergoing single-level ...
Kazuma Kitaguchi   +4 more
doaj   +1 more source

Polymeric Biomaterials for Topical Drug Delivery in the Oral Cavity: Advances on Devices and Manufacturing Technologies

open access: yesPharmaceutics, 2022
There are several routes of drug administration, and each one has advantages and limitations. In the case of the topical application in the oral cavity, comprising the buccal, sublingual, palatal, and gingival regions, the advantage is that it is ...
Paula de Freitas Rosa Remiro   +5 more
doaj   +1 more source

Effect of Topical Administration of Somatostatin on Retinal Inflammation and Neurodegeneration in an Experimental Model of Diabetes

open access: yesJournal of Clinical Medicine, 2020
Somatostatin (SST) is a neuroprotective peptide but little is known regarding the potential role of its anti-inflammatory effects on retinal neuroprotection.
C. Hernández   +6 more
semanticscholar   +1 more source

Effects of Combined Intralesional 5-Fluorouracil and Topical Silicone in Prevention of Keloids: A Double Blind Randomized Clinical Trial Study [PDF]

open access: yesActa Medica Iranica, 2011
Keloids are aesthetically disfiguring and severely disabling. The optimal treatment remains undefined. This clinical study, evaluate the efficacy and side effects of combined topical silicone and 5-Fluorouracil on the prevention of keloids.
Ebrahim Hatamipour   +3 more
doaj   +1 more source

Topical Ocular Administration of Progesterone Decreases Photoreceptor Cell Death in Retinal Degeneration Slow (rds) Mice

open access: yesPharmaceuticals, 2022
Retinitis pigmentosa (RP) is an inherited eye disorder which triggers a cascade of retinal disorders leading to photoreceptor cell death and for which there is currently no effective treatment.
Adrián M. Alambiaga-Caravaca   +4 more
doaj   +1 more source

Ropivacaine vs tetracaine in topical anesthesia for intravitreal injection [PDF]

open access: yes, 2015
Aim: The object of the study was to evaluate the long term efficacy and safety of ropivacaine 0,5% vs tetracaine 0,5% for topical anesthesia in intravitreal injection of dexamethasone in patients with diabetic macular edema (DME) and anti-vascular ...
COLLINI, Saul   +6 more
core   +1 more source

In Vivo Evaluation of Cefuroxime Axetil-Loaded Bioadhesive Nanoparticles to Treat Haemophilus influenzae-Induced Otitis Media

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
Otitis media (OM) is a common disease in children. One of the most common pathogens causing OM is non-typeable Haemophilus influenzae (NTHi). NTHi in the middle ear can be successfully eradicated by a regimen of oral antibiotics sustained for 7–10 days ...
Hong Lin   +6 more
doaj   +1 more source

Topical Administration of Terpenes Encapsulated in Nanostructured Lipid-Based Systems

open access: yesMolecules, 2020
Terpenes are a group of phytocompounds that have been used in medicine for decades owing to their significant role in human health. So far, they have been examined for therapeutic purposes as antibacterial, anti-inflammatory, antitumoral agents, and the ...
E. Lasoń
semanticscholar   +1 more source

mTHPC pharmacokinetics following topical administration [PDF]

open access: yesSPIE Proceedings, 2006
Measurements of concentration of sensitizers for photodynamic therapy can provide important information in the dosimetry planning and can also give input to the optimal time for treatment. There has been skepticism towards fluorescence techniques for this purpose, as the signal depends on the fluorescence yield and optical properties of the tissue ...
Johansson, Ann   +10 more
openaire   +2 more sources

Effects of Eye Drops Containing Hyaluronic Acid-Nimesulide Conjugates in a Benzalkonium Chloride-Induced Experimental Dry Eye Rabbit Model

open access: yesPharmaceutics, 2021
Dry eye syndrome (DES) is a common ocular disease worldwide. Currently, anti-inflammatory agents and immunosuppressive drugs, such as cyclosporine A, have been widely used to treat this chronic condition. However, the multifactorial etiology of DES, poor
Tzu-Yang Chen   +5 more
doaj   +1 more source

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