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There are several routes of drug administration, and each one has advantages and limitations. In the case of the topical application in the oral cavity, comprising the buccal, sublingual, palatal, and gingival regions, the advantage is that it is ...
Paula de Freitas Rosa Remiro+5 more
doaj +1 more source
Digital Divides and Online Media [PDF]
Digital divide has been a common concern during the past two or three decades; traditionally, it refers to a gap between developed and developing countries in the adoption and use of digital technologies. Given the importance of the topic, digital divide has been also extensively studied, although, hitherto, there is no previous research that would ...
arxiv +1 more source
Dry eye syndrome (DES) is a common ocular disease worldwide. Currently, anti-inflammatory agents and immunosuppressive drugs, such as cyclosporine A, have been widely used to treat this chronic condition. However, the multifactorial etiology of DES, poor
Tzu-Yang Chen+5 more
doaj +1 more source
Use of ozone-based eye drops. A series of cases in veterinary and human spontaneous ocular pathologies [PDF]
Conjunctivitis, keratoconjunctivitis, and corneal ulcers are common eye disorders frequently diagnosed in both humans and animals, and are currently treated by topical administration of eye drops containing anti-inflammatory and antibacterial agents. The
Marchegiani, Andrea+3 more
core +3 more sources
Melanoma is a highly lethal type of cancer that has had an increase in incidence in the last decades. Nevertheless, current therapies lack effectiveness and have highly disabling side effects, which calls for new therapeutic strategies.
Gabriel Martínez-Razo+5 more
doaj +1 more source
Antibacterial Effect of Topically Administered Tranexamic Acid in Large Joint Arthroplasty
Tranexamic acid (TXA) is a synthetic derivative of the amino acid lysine and is commonly used as an antifibrinolytic agent in large joint surgery, such as knee arthroplasty, to minimize blood loss and its associated complications.
Urban Slokar+3 more
doaj +1 more source
Breaking down the Barrier: Topical Liposomes as Nanocarriers for Drug Delivery into the Posterior Segment of the Eyeball [PDF]
Topical instillation is the most widely preferred noninvasive route of drug administration to treat diseases affecting the anterior segment of the eye. Nonetheless, the ocular bioavailability for deeper ocular tissues is very low.
Altamirano-Vallejo, Juan C.+4 more
core +1 more source
Graphene Oxide Topical Administration: Skin Permeability Studies [PDF]
Nanostructured carriers have been widely used in pharmaceutical formulations for dermatological treatment. They offer targeted drug delivery, sustained release, improved biostability, and low toxicity, usually presenting advantages over conventional formulations. Due to its large surface area, small size and photothermal properties, graphene oxide (GO)
Filipa A. L. S. Silva+9 more
openaire +4 more sources
Ice versus lidocaine 5% gel for topical anaesthesia of oral mucosa – a randomized cross-over study
Background Topical anaesthesia is important to optimize pain control during dental injection. Our aim was to describe a new simple method for topical anaesthesia of oral mucosa and to compare the effectiveness of ice and lidocaine 5% gel for topical ...
Nishma Hindocha+3 more
doaj +1 more source
Aims: The combined (IV (intravenous) + topical) use of tranexamic acid (TXA) has been shown to be a safe method and more effective than single (IV or topical) application.
Deniz Cankaya+5 more
doaj +1 more source