Results 61 to 70 of about 149,732 (304)

Artificial Intelligence–Based Online Symptom Assessment Tools for Systemic Lupus Erythematosus Diagnosis: Patient Perspectives

Arthritis Care &Research, EarlyView.
Objective The objective of this article is to identify perceptions of patients with systemic lupus erythematosus (SLE) regarding artificial intelligence (AI)–based online symptom assessment tools, and the potential of these tools to address diagnostic barriers.
Olivia A. Stein, Jennifer L. F. Lee, Evelyne Vinet, Arielle Mendel, Christian A. Pineau, Fares Kalache, Louis‐Pierre Grenier, Sasha Bernatsky   +7 more
wiley   +1 more source

Topical preparations for pain relief: efficacy and patient adherence

, 2010
Liliana L Jorge1,2, Caroline C Feres1, Vitor EP Teles31Lucy Montoro Institute of Rehabilitation, São Paulo, São Paulo, Brazil; 2Albert Einstein Jewish Hospital, São Paulo, São Paulo, Brazil; 3Ana Carolina Moura
Liliana L Jorge, Carol Campelo Feres, Vitor EP Teles, Liliana Lourenco Jorge, PR Telles-Dias, Caroline C Feres   +5 more
core   +1 more source

New cationic nanovesicular systems containing lysine-based surfactants for topical administration: Toxicity assessment using representative skin cell lines [PDF]

, 2013
Many strategies for treating diseases require the delivery of drugs into the cell cytoplasm following internalization within endosomal vesicles. Thus, compounds triggered by low pH to disrupt membranes and release endosomal contents into the cytosol are ...
Vinardell, M. Pilar, Morán, María del Carmen, Vinardell Martínez-Hidalgo, Ma. Pilar, Mitjans, Montserrat, Mitjans Arnal, Montserrat, Morán Badenas, María del Carmen, Pérez, Lourdes, Martínez Ocaña, Verónica, Nogueira, Daniele R., Nogueira, Daniele Rubert, Pérez Muñoz, Lourdes, Martínez, Verónica Laura   +11 more
core   +1 more source

Exploratory study on the efficacy of topical pan-JAK inhibitor in ocular and skin GVHD in a sclerodermatous GVHD mouse model

Scientific Reports
Systemic administration of Janus kinase (JAK) inhibitors is effective in treating chronic graft-versus-host disease (cGVHD) but is associated with side effects. Topical drug administration effectively minimizes side effects.
Shinri Sato, Yoko Ogawa, Kazuki Asai, Eisuke Shimizu, Shota Shimizu, Hiroko Taniguchi, Takahiro Okazaki, Shigeto Shimmura, Kazuno Negishi, Masatoshi Hirayama   +9 more
doaj   +1 more source

Design and development of artemisinin and dexamethasone loaded topical nanodispersion for the effective treatment of age‐related macular degeneration

IET Nanobiotechnology, 2019
Age‐related macular degeneration (AMD) is a disease affecting the macula by the new blood vessels formation. AMD is widely treated with a combination of anti‐angiogenic and anti‐vascular endothelial growth factor (VEGF) agents. The topical administration
Chandrasekar Ponnusamy, Abimanyu Sugumaran, Venkateshwaran Krishnaswami, Ruckmani Kandasamy, Subramanian Natesan   +4 more
doaj   +1 more source

A Knowledge‐Based Approach for Understanding and Managing Additive Manufacturing Data

Advanced Engineering Materials, EarlyView.
Additive manufacturing processes generate a large amount of data. Effectively managing, understanding, and retrieving information from this data remains a major challenge. Therefore, we propose an ontology‐based approach to integrate heterogeneous data, enable semantic queries, and support decision‐making.
Mina Abd Nikooie Pour, Prithwish Tarafder, Anton Wiberg, Huanyu Li, Johan Moverare, Patrick Lambrix   +5 more
wiley   +1 more source

Atopic dermatitis: a review of topical nonsteroid therapy

, 2018
Background: Atopic dermatitis is a chronic inflammatory skin condition that affects up to 20% of children and 3% of adults globally. Although topical corticosteroids are considered to be the first-line agents, they can be associated with cutaneous and ...
Lindsay C Strowd, Ariana Papier
core   +1 more source

Topical Remedies for the Treatment of Men’s Sexual Dysfunction from the Perspective of Traditional Persian Medicine: A Review Article [PDF]

Journal of Health Sciences and Surveillance System
Background: Sexual dysfunction is one of the most prevalent complaints in men over 50 years old, which can negatively affect marital life and self-esteem.
Abdolreza Haghpanah, Amir Mohammad Jaladat, Fatemeh Atarzadeh, Amirhossein Hassani, Elham Akbarzadeh, Mohammad Mahdi Parvizi   +5 more
doaj   +1 more source

Rafting of Ni‐Based Superalloys Under Multiaxial Load as Understood by Phase‐Field Simulations and Critical Experiments

Advanced Engineering Materials, EarlyView.
Phase‐field simulations coupled with dislocation‐density‐based crystal plasticity modeling reproduce γ′ rafting behavior in single‐crystal Ni‐based superalloys under varied loading conditions. The model captures both macroscopic creep and microscopic morphology evolution, with results matching high‐temperature creep experiments.
Micheal Younan, David Bürger, Gunther Eggeler, Oleg Shchyglo, Ingo Steinbach, Muhammad Adil Ali   +5 more
wiley   +1 more source

Improved Biosafety and Transdermal Delivery of Aconitine via Diethylene Glycol Monoethyl Ether-Mediated Microemulsion Assisted with Microneedles

Pharmaceutics, 2020
In the current study, diethylene glycol monoethyl ether-mediated microemulsions were combined with microneedles for enhanced transdermal aconitine delivery.
Yongtai Zhang, Hongmei Hu, Qian Jing, Zhi Wang, Zehui He, Tong Wu, Nian-Ping Feng   +6 more
doaj   +1 more source