Results 81 to 90 of about 2,655,093 (273)

Preparation and Evaluation of Glutathione Semisolid Formulation as a Candidate for Anti-wrinkle and Skin-Lightening [PDF]

مجله علوم پزشکی صدرا
Introduction: In recent years, there has been a growth in the demand for skincare services and products. In this study, a topical formulation composed of glutathione loaded into niosomes was developed, and its physical, chemical, and microbial ...
Mohammad-Mehdi Khazaei, Negin Mozafari, Soliman Mohammadi-Samani, Hajar Ashrafi, Amir Azadi   +4 more
doaj   +1 more source

Topical Administration of a Soluble TNF Inhibitor Reduces Infarct Volume After Focal Cerebral Ischemia in Mice

Frontiers in Neuroscience, 2019
Background Tumor necrosis factor, which exists both as a soluble (solTNF) and a transmembrane (tmTNF) protein, plays an important role in post-stroke inflammation.
M. Yli-Karjanmaa, B. Clausen, M. Degn, H. Novrup, D. Ellman, P. Toft-Jensen, David Edmund Szymkowski, A. Stensballe, M. Meyer, R. Brambilla, K. Lambertsen   +10 more
semanticscholar   +1 more source

Scabies: Application of the Novel Identify-Isolate-Inform Tool for Detection and Management [PDF]

, 2020
Scabies is a highly contagious, globally prevalent, parasitic skin infestation caused by Sarcoptes scabiei var. hominis, also known as the itch mite.
Al-Wabel, Abdussalam, Almutairi, Bandar Saad, Alsugair, Abdulrahman, Cheng, Tabitha, Kahn, Christopher A., Koenig, Kristi L., Maysa, Eshmawi, Mzahim, Bandr   +7 more
core  

NGX-4010, a capsaicin 8% patch, for the treatment of painful HIV-associated distal sensory polyneuropathy: integrated analysis of two phase III, randomized, controlled trials [PDF]

, 2013
BACKGROUND HIV-associated distal sensory polyneuropathy (HIV-DSP) is the most frequently reported neurologic complication associated with HIV infection.
Brew, Bruce J, Brown, Stephen, Fisher, Martin, Larbalestier, Nicholas, Moyle, Graeme, Orkin, Chloe, Schifitto, Giovanni, Simpson, David M, Tobias, Jeffrey K, Vanhove, Geertrui F   +9 more
core   +1 more source

A Randomized, Double-Blinded, Placebo-Controlled, Cross Over Study Evaluating the Efficacy and Safety of Timolol Ophthalmic Solution as an Acute Treatment of Migraine [PDF]

, 2020
Introduction. Daily oral beta-adrenoreceptor antagonist has been shown to be effective in preventing migraine headaches. Timolol 0.5% ophthalmic solution is a non-selective beta-adrenoreceptor antago- nist, where the primary use is for glaucoma.
Aggarwal, Dipika, Barohn, Richard J., Bittel, Brennen, Dubinsky, Richard, Ford, Deetra, Gronseth, Gary, Hairston, Vernita, Heim, Andrew J., Herbelin, Laura, Landazuri, Patrick, Sachen, Fred   +10 more
core   +2 more sources

Central Serous Chorioretinopathy in a 14-year-old atopic boy: a case report

Italian Journal of Pediatrics, 2023
Background Corticosteroids are widely used in medicine. Few cases of central serous chorioretinopathy (CSC) have been reported following topical corticosteroid administration.
Stefano Ranno, Liviana Fontanel, Edoardo Ruggiero, Paolo Nucci, Paolo Radice, Simone Donati   +5 more
doaj   +1 more source

mRNA-Based Nanomedicinal Products to Address Corneal Inflammation by Interleukin-10 Supplementation

Pharmaceutics, 2021
The anti-inflammatory cytokine Interleukin-10 (IL-10) is considered an efficient treatment for corneal inflammation, in spite of its short half-life and poor eye bioavailability. In the present work, mRNA-based nanomedicinal products based on solid lipid
Itziar Gómez-Aguado, Julen Rodríguez-Castejón, Marina Beraza-Millor, Mónica Vicente-Pascual, Alicia Rodríguez-Gascón, Sara Garelli, Luigi Battaglia, Ana del Pozo-Rodríguez, María Ángeles Solinís   +8 more
doaj   +1 more source

Topical Administration of Bosentan Prevents Retinal Neurodegeneration in Experimental Diabetes

International Journal of Molecular Sciences, 2018
Experimental evidence suggests that endothelin 1 (ET-1) is involved in the development of retinal microvascular abnormalities induced by diabetes. The effects of ET-1 are mediated by endothelin A- and B-receptors (ETA and ETB).
P. Bogdanov, O. Simó-Servat, J. Sampedro, Cristina Solà-Adell, M. García-Ramírez, H. Ramos, M. Guerrero, J. Suñe-Negre, J. Ticó, B. Montoro, Vicente Durán, L. Arias, C. Hernández, R. Simó   +13 more
semanticscholar   +1 more source

An Evaluation of the in vivo Safety of Nonporous Silica Nanoparticles: Ocular Topical Administration versus Oral Administration

Scientific Reports, 2017
Nonporous silica nanoparticles (SiNPs) have potential as promising carriers for ophthalmic drugs. However, the in vivo safety of ocular topical SiNPs remains unclear.
Martha A. Kim, J. Park, Hyejoong Jeong, Jinkee Hong, Woo Sung Choi, Byung-Han Lee, Choul-Yong Park   +6 more
semanticscholar   +1 more source

Exploratory study on the efficacy of topical pan-JAK inhibitor in ocular and skin GVHD in a sclerodermatous GVHD mouse model

Scientific Reports
Systemic administration of Janus kinase (JAK) inhibitors is effective in treating chronic graft-versus-host disease (cGVHD) but is associated with side effects. Topical drug administration effectively minimizes side effects.
Shinri Sato, Yoko Ogawa, Kazuki Asai, Eisuke Shimizu, Shota Shimizu, Hiroko Taniguchi, Takahiro Okazaki, Shigeto Shimmura, Kazuno Negishi, Masatoshi Hirayama   +9 more
doaj   +1 more source