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Topical ophthalmic anesthetics for corneal abrasions
Cochrane Database of Systematic Reviews, 2023Despite potential analgesic benefits from topical ophthalmic amides and esters, their outpatient use has become of concern because of the potential for abuse and ophthalmic complications.To assess the effectiveness and safety of topical ophthalmic anesthetics compared with placebo or other treatments in persons with corneal abrasions.We searched the ...
Michael, Sulewski +5 more
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Evaluation of a Topical Anesthetic --Dyclonine
Archives of Otolaryngology - Head and Neck Surgery, 1961Numerous reports relate the ill effects of commonly used topical anesthetic agents, although probably only a small percentage of such mishaps are reported. 1 We thus felt it of value to appraise a relatively new compound, dyclonine,* which reportedly has a wide margin of safety. Clinically the drug has been used in the eye, mouth, bronchi, urethra, and
D O, MERIFIELD, E E, JOHNSON
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Methemoglobinemia From Topically Applied Anesthetic Spray
Mayo Clinic Proceedings, 1994Topically applied anesthetic spray is commonly used as part of premedication for general anesthesia and for endoscopic procedures; it is rarely associated with side effects. In this report, we describe two cases of toxic methemoglobinemia that resulted from topically applied anesthetic spray used before endoscopy.
S F, Dinneen, D N, Mohr, V F, Fairbanks
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Methemoglobinemia induced by topical anesthetic (benzocaine)
Radiotherapy and Oncology, 1990Methemoglobinemia is a condition in which more than 2% of the hemoglobin of the blood has been oxidized to the ferric form, a molecule which is incapable of binding oxygen or carbon dioxide. Clinically, the patient appears lethargic, cyanotic, and does not respond to oxygen.
L A, Linares, T Y, Peretz, J, Chin
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Pain produced by topical anesthetic ointment
Dental Traumatology, 1987Abstract Lidocaine ointment applied topically to gingivae of vital teeth with exposed dentin caused acute, severe pain. Measurement of the osmotic pressure of the ointment revealed that it was very hypertonic, due mainly to the high concentration of polyethylene glycol vehicle. The results support the hydrodynamic theory of dentin sensitivity.
D H, Pashley, G S, Parsons
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Topical anesthetics for pediatric laser treatment
Journal of Cosmetic and Laser Therapy, 2019Topical anesthetic agent causes transient insensibility to pain in a limited area of skin, and provides effective anesthesia in a short onset time, short duration, with seldom local or systemic side effects on intact skin and is simple to use. Topical formulations may offer significant benefits for prevention of procedural pain.
Marija, Stevic +8 more
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2018
Abstract Local anesthesia is an important part of pediatric procedural sedation. Not only does it allow for pain reduction during intravenous catheter placement, but it can also reduce the total amount of sedation that is required during painful procedures and minimize the need for postoperative analgesia.
Amy E. Vinson, Constance S. Houck
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Abstract Local anesthesia is an important part of pediatric procedural sedation. Not only does it allow for pain reduction during intravenous catheter placement, but it can also reduce the total amount of sedation that is required during painful procedures and minimize the need for postoperative analgesia.
Amy E. Vinson, Constance S. Houck
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The Antibacterial Activity of Topical Anesthetics
Cornea, 1997Topical anesthetics are commonly used prior to obtaining bacterial cultures in ulcerative keratitis. We performed an in vitro study designed to test both the bacteriostatic and bactericidal effects of commercially available preserved topical anesthetic agents.Proparacaine, tetracaine, cocaine, and sterile water solutions were applied to filter paper ...
G S, Mullin, R S, Rubinfeld
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Diphenhydramine as a topical ocular anesthetic
Canadian Journal of Ophthalmology, 2009To determine whether 5% diphenhydramine solution has an anesthetic effect when administered topically to rabbit corneas.Experimental study.Twenty white New Zealand rabbits.Twenty rabbits at the University of Arkansas for Medical Sciences received 1 drop of 5% diphenhydramine solution in the left eye and 1 drop of balanced salt solution in the right eye.
Phillip J, Suffridge +3 more
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