Wound closure is governed by geometry‐orientation coupling: aligned fibers speed migration along their axis but hinder perpendicular advance. In vivo diabetic wound experiments with composition‐matched fibrin, combined with an anisotropic diffusion (biased random‐walk) model, quantify this trade‐off and generate a healing landscape.
Yin‐Yuan Huang +13 more
wiley +1 more source
Supersaturation as a Galenic Concept for Improving the Cutaneous Bioavailability of Drugs in Topical Therapy. [PDF]
Wohlrab J, Eichner A.
europepmc +1 more source
Flexible Polypyrrole‐Based pH Sensors via Oxidative Chemical Vapor Deposition
Oxidative chemical vapor deposition (oCVD) of polypyrrole (PPy) thin films yields flexible, electrically conductive, and biocompatible pH sensors for monitoring on‐skin biological events. The highly sensitive, oCVD PPy skin‐conformal sensors enable real‐time, spatially resolved sensing of dynamic pH changes within physiologically relevant ranges (4–9 ...
Adrivit Mukherjee +15 more
wiley +1 more source
Tapinarof cream 1% once daily for the treatment of adults with mild to severe plaque psoriasis: A novel topical therapy targeting the aryl hydrocarbon receptor. [PDF]
Armstrong AW, McConaha JL.
europepmc +1 more source
xx xx. ABSTRACT Stimuli‐responsive nanomaterials capable of spatiotemporal control over drug release are of nanocomposite patch (“e‐Medi‐Patch”) engineered from biodegradable polycaprolactone (PCL), graphene nanoplatelets, and a redox‐active therapeutic, niclosamide. The hierarchical composite integrates π‐π interactions between aromatic drug molecules
Santosh K. Misra +7 more
wiley +1 more source
New Topical Therapy for Provoked Vestibulodynia: Improvement of Psychological and Sexual Well-Being. [PDF]
De Seta F +5 more
europepmc +1 more source
Controllable Dynamic Mechanical Cell Stimulation using Magnetically Actuated Artificial Cilia
This paper introduces a platform based on magnetic artificial cilia for providing controllable dynamic mechanical stimulation to single cells, suitable for investigating large cell populations and enabling live cell imaging. Proof‐of‐principle experiments show that cell morphology is strongly influenced by the artificial cilia, that cellular forces can
Roel Kooi +5 more
wiley +1 more source
The role of endoscopic management and adjuvant topical therapy for upper tract urothelial cancer. [PDF]
Chien AL +3 more
europepmc +1 more source
Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa +3 more
wiley +1 more source
George P Christophi, Arvind Rengarajan, Matthew A Ciorba Division of Gastroenterology, Washington University School of Medicine, St.
Christophi GP, Rengarajan A, Ciorba MA
doaj

