Results 71 to 80 of about 309,670 (308)
Matrix Metalloproteinases and Glaucoma Treatment. [PDF]
, 2020 Matrix metalloproteinases (MMPs) are a family of proteolytic enzymes that degrade extracellular matrix (ECM) components such as collagen and have important roles in multiple biological processes, including development and tissue remodeling, both in ...
Dibas, Mohammed +3 more
core
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Plasma total antioxidant capacity and peroxidation biomarkers in psoriasis [PDF]
, 2016 Systemic biomarkers of oxidative stress can be relevant for assessment of psoriasis severity, for prediction of the outcome of therapy and of the development of comorbidities.
Cavaliere, Arturo +2 more
core +2 more sources
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Journal of Dermatological TreatmentObjective Effective systemic treatments for psoriasis may reduce the need for topical therapies. The objective of this study was to evaluate changes in topical prescriptions after apremilast initiation.Materials and methods This retrospective cohort ...
Siddharth Chaudhari +5 more
doaj +1 more source
Topical Therapies for Pruritus [PDF]
Seminars in Cutaneous Medicine and Surgery, 2011 Itch, or pruritus, is the predominant symptom associated with acute and chronic cutaneous disease, and in some cases may be debilitating. To date, there is no single universally effective anti-itch treatment. Because the pathophysiology of itch in most cutaneous or systemic disorders remains unclear, antipruritic therapy is often directed against a ...
Sarina B, Elmariah, Ethan A, Lerner
openaire +2 more sources
Pro-Secretory Activity and Pharmacology in Rabbits of an Aminophenyl-1,3,5-Triazine CFTR Activator for Dry Eye Disorders. [PDF]
, 2017 PurposePharmacological activation of ocular surface cystic fibrosis transmembrane conductance regulator (CFTR) chloride channels is a potential pro-secretory approach to treat dry eye disorders.
Felix, Christian M +3 more
core +2 more sources
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
The efficiency of topical therapy and prevention of inflammatory diseases of the pharynx
Медицинский совет, 2018 Today, one of the most frequent causes for visiting paediatricians, general practitioners, ENT specialists are infectious inflammatory diseases of the pharynx [1].
S. V. Ryazantsev, P. A. Shamkina
doaj +1 more source
Nanoemulsions: colloidal topical delivery systems for antiacne agents- A Mini-Review [PDF]
Nanomedicine Research Journal, 2017 One of the common chronic inflammatory skin diseases is Acne Vulgaris that affects up to 80% of a teen-age population. The progress of acne lesions is due to colonization of Propionibacterium acnes (P .acnes) in hair follicles. Treatment of acne includes
Roqya Najafi-Taher, Amir Amani
doaj +1 more source