Retrospective, Multicenter Study of Lacosamide to Treat Neonatal Seizures
ABSTRACT Objective Most antiseizure medications (ASMs) are prescribed off label for neonates. Lacosamide's efficacy in infants and availability in intravenous formulation suggest potential utility for neonates. We evaluated the safety and efficacy of lacosamide for neonatal seizures. Methods This 10‐center, retrospective study of neonates with seizures
Alexandra Santana Almansa +15 more
wiley +1 more source
Pharmacotherapy for Alcohol Craving Reduction: Efficacy of Short-Term Treatments in Alcohol Use Disorder. [PDF]
Cheibub David Marin M +3 more
europepmc +1 more source
Obesity and Natural Products: Mechanisms, Therapeutic Potential, and Future Directions
Natural products such as EGCG, berberine, curcumin, and capsaicin modulate key metabolic pathways including AMPK activation, adipogenesis inhibition, and inflammatory signaling. While clinical trials demonstrate modest benefits on body weight and metabolic parameters, translational challenges related to bioavailability, dose feasibility, and regulatory
Ohoud M. Marie +1 more
wiley +1 more source
Persistent genital arousal symptoms in a young woman with recurring brief psychoses: a clinical dilemma in antipsychotic choice. [PDF]
Fortin-Latour É, Stip E.
europepmc +1 more source
Anticonvulsant Therapy in Trigeminal Neuralgia: A Class-Oriented Systematic Review. [PDF]
Pinto Moreira M +4 more
europepmc +1 more source
When Recurrent Pancreatitis Is Not Pancreatitis: Cyclic Vomiting Syndrome Masquerading as Acute Pancreatitis in a Young Adult. [PDF]
Ottu Para NK +2 more
europepmc +1 more source
Abstract Aim To examine the socioeconomic differences in the effectiveness of alcohol use disorders (AUD) pharmacotherapy and risk of AUD hospitalisation. Design A prospective register‐based cohort study. Setting Sweden. Participants Individuals who were registered as living in Sweden in 2005 (16–64 years) with a first‐time AUD diagnosis and complete ...
Devy L. Elling +6 more
wiley +1 more source
Abstract Aims To assess the real‐world effectiveness of semaglutide versus tirzepatide in reducing major adverse cardiovascular events (MACE) among patients with overweight/obesity and established atherosclerotic cardiovascular disease (ASCVD) without diabetes in an insured US population.
Lauren Wilson +6 more
wiley +1 more source
Medical Management of Obesity: A Comprehensive Review of Food and Drug Administration (FDA)-Approved and Investigational Therapies. [PDF]
Raza SS +4 more
europepmc +1 more source
Predominant Symptom in Gastroparesis: Relationships to Quality of Life, Treatments, and Outcome
In patients with gastroparesis, the most common predominant symptoms were nausea, vomiting, and abdominal pain. Impaired QOL varied with patients' predominant symptom, with abdominal pain associated with poorer QOL. Over 48 weeks, GSCI improved ≥ 1 in a minority of patients, more often in patients with predominant symptoms of nausea and bloating, less ...
Henry P. Parkman +16 more
wiley +1 more source

