Results 41 to 50 of about 6,615,362 (295)

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

The topographic-based v s30 model of the Opak River basin Yogyakarta

Geoenvironmental Disasters
Background Accurate v s30 values are crucial for earthquake hazard assessment. The ongoing development of the v s30 Model aims to yield the most precise representation of field conditions.
Nugroho Budi Wibowo, Teuku Faisal Fathani, Subagyo Pramumijoyo, Gayatri Indah Marliyani   +3 more
doaj   +1 more source

Topographic Gradient Differentiation and Ecological Function Zoning Based on Ecosystem Services: A Case Study of Fuping County

Nature Environment and Pollution Technology, 2023
Scientifically delineating ecological function zones is essential for national territory spatial planning and comprehensive management. In this study, we evaluated five ecosystem services, habitat quality, water yield, carbon sequestration, soil ...
Ling He, Zhe Du, Jia-wei Tian, Shu-Qi Chen   +3 more
semanticscholar   +1 more source

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

GIS-based landform and LULC classifications in the Sub-Himalayan Kaljani Basin: Special reference to 2016 Flood

Egyptian Journal of Remote Sensing and Space Sciences, 2021
Progress in GIS technology has facilitated the topographic position index (TPI)-based auto-classification of landform units. Multispectral satellite images, when used along with terrain analysis output, provide valuable information on structure, soil ...
Lopamudra Roy, Sayantan Das
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Geospatial Modelling of Flood Susceptibility of the Calabar City, Cross River State, Nigeria

Applied Environmental Research
Flooding remains a major environmental problem in many parts of the world including Nigeria, causing untold losses. This study modelled the flood susceptibility of Calabar Metropolis using frequency ratio and geographical information system (GIS ...
Joel Efiong, Eme Efiong, Oluyemi Akintoye, Ebin Inah, Obianuju Awan, Francis Ogban   +5 more
doaj   +3 more sources

Landscape Ecological Risk and Drivers of Land-Use Transition under the Perspective of Differences in Topographic Gradient

Land
Human activities have caused different degrees of land-use change on different topographic gradients, with impacts on the landscape and ecosystem. Effectively preventing and addressing ecological risk (ER) and achieving harmonious coexistence between ...
Xuebin Zhang, Jiale Yu, Haoyuan Feng, Litang Yao, Xuehong Li, Hucheng Du, Yanni Liu   +6 more
doaj   +1 more source

Topographic control of snowpack distribution in a small catchment in the central Spanish Pyrenees: intra- and inter-annual persistence [PDF]

The Cryosphere, 2014
In this study we analyzed the relations between terrain characteristics and snow depth distribution in a small alpine catchment located in the central Spanish Pyrenees.
J. Revuelto, J. I. López-Moreno, C. Azorin-Molina, S. M. Vicente-Serrano   +3 more
doaj   +1 more source