Results 131 to 140 of about 69,479 (251)

Detection of Diagnostic Antibodies in Immune‐Mediated Diseases: A Focus on Antigens and Technologies

open access: yesChemBioChem, Volume 27, Issue 9, 14 May 2026.
This review explores autoantibody detection in immune‐mediated diseases, highlighting autoantigens including post‐translational modifications. We compared enzyme‐linked immunosorbent assay and indirect immunofluorescence with automated chemiluminescence platforms.
Silvia Bracci   +5 more
wiley   +1 more source

What is a supercoiling-sensitive gene? Insights from topoisomerase I inhibition in the Gram-negative bacterium Dickeya dadantii. [PDF]

open access: yesNucleic Acids Res, 2022
Pineau M   +11 more
europepmc   +1 more source

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

open access: yesAdvanced Functional Materials, Volume 36, Issue 36, 4 May 2026.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley   +12 more
wiley   +1 more source

Targeting the nuclear export receptor exportin‐1 in acute myeloid leukaemia: From biology to clinical translation

open access: yesClinical and Translational Medicine, Volume 16, Issue 5, May 2026.
• XPO1 hyperactivation promotes leukaemogenesis by altering nucleocytoplasmic transport and transcriptional control in acute myeloid leukaemia (AML). • Selinexor and eltanexor show preferential activity in NPM1‐mutated, DEK::NUP214‐positive and SF3B1‐mutated myeloid neoplasms.
Yifan Liu   +4 more
wiley   +1 more source

Traits Explain Canopy Tree Occurrence Along Regional Environmental Gradients: A Subset Combine to Be Useful

open access: yesEcology and Evolution, Volume 16, Issue 5, May 2026.
Our paper addresses the problem of “How to predict where a tree can be found from its traits?” We show that wood density, bark thickness, maximum height and seed mass combine for a useful model of tree distributions. ABSTRACT Trait‐Species Distribution Models (trait‐SDM) help to understand the importance of plant strategies to niches, assess their ...
Peter A. Vesk   +6 more
wiley   +1 more source

Geodiversity is an inseparable but underutilized aspect of ecological connectivity assessments under climate change

open access: yesEcography, Volume 2026, Issue 5, May 2026.
Conservation has shifted towards a climate change adaptation approach in which expected species range shifts are increasingly considered to mitigate effects of climate change and habitat fragmentation on biodiversity. As part of this, ecological connectivity needs to be ensured to support gene flow and viable populations in the face of changing ...
Aino‐Maija Määttänen   +2 more
wiley   +1 more source

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