Results 211 to 220 of about 11,228 (296)

Regulation of PHOX2B gene expression by the long non‐coding natural antisense RNA PHOX2B‐AS1

The FEBS Journal, Volume 293, Issue 12, Page 3502-3527, June 2026.
PHOX2B is a transcription factor essential for autonomic nervous system development. We identify and characterize PHOX2B‐AS1, a human long non‐coding antisense transcript at the PHOX2B locus, along with its murine counterpart. Our findings reveal bidirectional transcription and reciprocal regulation: PHOX2B activates PHOX2B‐AS1, whereas PHOX2B‐AS1 ...
Simona Di Lascio, Ana Lucia Cuadros Gamboa, Martina Bertocchi, Filippo Chiesa, Francesca Cargnin, Ettore Mosca, Paride Pelucchi, Viviana Tritto, Stefania Corti, Isabella Ceccherini, Paola Riva, Roberta Benfante, Diego Fornasari   +12 more
wiley   +1 more source

Predictive Value of the DETECT Algorithm for Pulmonary Arterial Hypertension in Systemic Sclerosis: Findings from an Italian Observational Study. [PDF]

J Clin Med
Stano S, Iannone C, D'Agostino C, Pellico MR, Urso L, Del Papa N, Caporali R, Cacciapaglia F.   +7 more
europepmc   +1 more source

Humanized Antibodies Targeting Ectodomains of IL‐6R and GP130 Suppress IL‐6/STAT3 Signalling and Tumour Growth in Breast Cancer Models

Journal of Cellular and Molecular Medicine, Volume 30, Issue 12, June 2026.
ABSTRACT Interleukin‐6 (IL‐6) signalling is a key driver of breast cancer progression, activating pro‐survival, pro‐inflammatory and metastatic programs through its receptors, IL‐6R and GP130. Elevated IL‐6 levels correlate with poor prognosis in breast cancer patients and persistent IL‐6/STAT3 activation promotes tumour proliferation, metastasis ...
Satyajit Dey Pereira, Guruprasad Baipadithaya, Keshava Prasad, Ritam Naha, Lavanya Prakash Acharya, Ganesh Prasad Uppenda Gopalakishna, Ramyaa Periasamy, Arun Chandrashekar, Shama Bhat, Manjunath B. Joshi, Kapaettu Satyamoorthy   +10 more
wiley   +1 more source

Critical Contextual Empiricism for Busy People: Scientific Argumentation as Epistemic Exchange. [PDF]

Topoi (Dordr)
Dutilh Novaes C, Dede Ç.
europepmc   +1 more source

Class Struggle, Commodity Fetishism, and Historical Materialism in the New Latin American Cinema

Sociology Lens, Volume 39, Issue 2, Page 327-335, June 2026.
ABSTRACT This study examines Latin American cinema after the 2010s through the concepts of class struggle, commodity fetishism, and historical materialism. The study aims to discuss how the region's colonial legacy, neoliberal policies, and current political transformations are reproduced in cinematic narratives.
Doğuşcan Göker, Muzaffer Musab Yılmaz   +1 more
wiley   +1 more source

An antiviral jacalin‐like lectin gene contributes to nonhost resistance and host determination of potexviruses among Brassicaceae

New Phytologist, Volume 250, Issue 5, Page 3283-3298, June 2026.
Summary Plant resistance influences the host range of pathogens; however, the mechanism driving this influence remains poorly understood. Brassicaceae species are not natural hosts of potexviruses, for reasons that have not yet been determined. This study investigated the molecular basis of nonhost resistance (NHR) to potexviruses in the Brassicaceae ...
Takumi Suzuki, Kazuya Ishikawa, Akira Yusa, Nozomu Iwabuchi, Kan Kimura, Tetsuya Yoshida, Mari Ota, Masato Suzuki, Masanobu Nishikawa, Kensaku Maejima, Shigetou Namba, Yasuyuki Yamaji   +11 more
wiley   +1 more source

A Novel Sesterterpenoid, Petrosaspongin and γ-Lactone Sesterterpenoids with Leishmanicidal Activity from Okinawan Marine Invertebrates. [PDF]

Mar Drugs
Jomori T, Higa N, Hokama S, Tyas TA, Matsuura N, Ueda Y, Kimura R, Arizono S, de Voogd NJ, Hayashi Y, Yasumoto-Hirose M, Tanaka J, Mori-Yasumoto K.   +12 more
europepmc   +1 more source

Cyclophilin A‐mediated cis/trans isomerization modulates RIN4 to control intracellular rhizobial infection in legumes

New Phytologist, Volume 250, Issue 6, Page 3932-3945, June 2026.
Summary In most legume‐rhizobium symbioses, rhizobial colonization occurs through host‐derived intracellular infection threads, which enable rhizobial recruitment while presumably modulating the host immune system to prevent rejection. To investigate post‐translational regulation of immune responses during rhizobial infection, we focused on Cyclophilin
Takashi Goto, Kasper Røjkjær Andersen, Masaru Bamba, Shusei Sato, Masayuki Sugawara, Kiwamu Minamisawa, Masayoshi Kawaguchi, Jens Stougaard, Yasuyuki Kawaharada   +8 more
wiley   +1 more source

Host‐Induced Silencing of Rhizoctonia Solani 5‐Enolpyruvylshikimate‐3‐Phosphate Synthase Impairs Its Virulence in Rice

Plant Biotechnology Journal, Volume 24, Issue 6, Page 3573-3593, June 2026.
ABSTRACT Sheath blight disease of rice caused by the fungal pathogen R. solani AG1‐IA remains a big threat to rice production worldwide. A limited genetic variation in rice for tolerance to this pathogen and little success in understanding how it defeats host defence are major reasons behind it.
Vinod Kumar, Apoorva Prasad, Akshita Goel, Vijay Kumar Sharma, Jagjeet Singh Lore, Arun Kumar   +5 more
wiley   +1 more source

Truthmaker Semantics for Intuitionistic Modal Logic. [PDF]

Topoi (Dordr)
Litland JE.
europepmc   +1 more source