Results 221 to 230 of about 6,410,919 (241)

AK-I-190, a New Catalytic Inhibitor of Topoisomerase II with Anti-Proliferative and Pro-Apoptotic Activity on Androgen-Negative Prostate Cancer Cells

International Journal of Molecular Sciences, 2021
Eung-Seok Lee, Youngjoo Kwon, Soo-Yeon Hwang   +2 more
exaly  

Actions of a Novel Bacterial Topoisomerase Inhibitor against Neisseria gonorrhoeae Gyrase and Topoisomerase IV: Enhancement of Double-Stranded DNA Breaks

International Journal of Molecular Sciences, 2023
Jack Yalowich, Neil Osheroff, Jessica Collins   +2 more
exaly  

Identification of a novel catalytic inhibitor of topoisomerase II alpha that engages distinct mechanisms in p53 or p53 cells to trigger G2/M arrest and senescence

Cancer Letters, 2022
Shazib Pervaiz, Karishma Sachaphibulkij, Jayshree L Hirpara   +2 more
exaly  

High Antitumor Activity of the Dual Topoisomerase Inhibitor P8-D6 in Breast Cancer

Cancers, 2022
Flörkemeier Inken, Dirk O. Bauerschlag, Jörg Weimer   +2 more
exaly  

Immunogenic Cell Death by the Novel Topoisomerase I Inhibitor TLC388 Enhances the Therapeutic Efficacy of Radiotherapy

Cancers, 2021
Yi-Wen Huang, Chih-Yang Huang, Shu-Fen Chiang   +2 more
exaly  

2070-DTI, A Topoisomerase Inhibitor Produced by Streptomyces sp. Strain No. 2070

Journal of Enzyme Inhibition and Medicinal Chemistry, 2003
Shoji Yahara, Keitarou Suzuki, Satoru Doi   +2 more
exaly  

A novel epoxypropoxy flavonoid derivative and topoisomerase II inhibitor, MHY336, induces apoptosis in prostate cancer cells

European Journal of Pharmacology, 2011
Hyung Sik Kim, Hae Young Chung, Jee H Jung   +2 more
exaly  

Phase I and pharmacokinetic study of the topoisomerase I inhibitor, exatecan mesylate (DX-8951f), using a weekly 30-minute intravenous infusion, in patients with advanced solid malignancies

Annals of Oncology, 2003
D C Talbot, H M Pinedo
exaly  

3-(3-Butylamino-2-hydroxy-propoxy)-1-hydroxy-xanthen-9-one acts as a topoisomerase IIα catalytic inhibitor with low DNA damage

European Journal of Medicinal Chemistry, 2013
Eunyoung Lee, Eung-Seok Lee, Youngjoo Kwon   +2 more
exaly