Results 31 to 40 of about 55,932 (263)

Topological sensitivity based far-field detection of elastic inclusions

Results in Physics, 2018
The aim of this article is to present and rigorously analyze topological sensitivity based algorithms for detection of diametrically small inclusions in an isotropic homogeneous elastic formation using single and multiple measurements of the far-field ...
Tasawar Abbas, Shujaat Khan, Muhammad Sajid, Abdul Wahab, Jong Chul Ye   +4 more
doaj   +1 more source

Topological Obstructions to Stability and Stabilization

, 2023
This open access book provides a unified overview of topological obstructions to the stability and stabilization of dynamical systems defined on manifolds and an overview that is self-contained and accessible to the control-oriented graduate student. The authors review the interplay between the topology of an attractor, its domain of attraction, and ...
Wouter Jongeneel, Emmanuel Moulay
openaire   +3 more sources

Cubic Hafnium Nitride: A Novel Topological Semimetal Hosting a 0-Dimensional (0-D) Nodal Point and a 1-D Topological Nodal Ring

Frontiers in Chemistry, 2020
Very recently, topological semimetals with nontrivial band crossing and associated topological surface states have received widespread attention. Various types of topological semimetals, including nodal point semimetals, nodal line semimetals, and nodal ...
Yang Li, Yang Li, Jihong Xia
doaj   +1 more source

A topological characterization of stabilizing consensus

Distributed Computing
Abstract We provide a complete characterization of the solvability/impossibility of deterministic stabilizing consensus in virtually any computing model with benign process and communication faults using point-set topology. Relying on the topologies for infinite executions introduced by Nowak, Schmid and Winkler (JACM, 2024) for ...
Ulrich Schmid, Stephan Felber, Hugo Rincon Galeana   +2 more
openaire   +2 more sources

Soliton stability and topological invariants in a generalized nonlinear Klein–Gordon equation: Existence, dynamics, and conservation laws

Nonlinear Analysis
This paper investigates the stability and dynamical behavior of soliton solutions in generalized nonlinear Klein–Gordon equations defined on higher-dimensional manifolds. We establish the existence of stable multisoliton configurations using variational
José Luis Díaz Palencia
doaj   +1 more source

Implications of Network Topology on Stability

PLOS ONE, 2015
In analogy to chemical reaction networks, I demonstrate the utility of expressing the governing equations of an arbitrary dynamical system (interaction network) as sums of real functions (generalized reactions) multiplied by real scalars (generalized stoichiometries) for analysis of its stability.
openaire   +5 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

FEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima, Gustavo Narvaes Guimarães, Emilyane de Oliveira Santana Amaral, Bianca Caroline Figueiredo Bianco, Manuel Jara‐Espejo, Sérgio Roberto Peres Line, Ana Paula de Souza, Aline Cristiane Planello   +7 more
wiley   +1 more source