Results 141 to 150 of about 2,242 (239)

The SVP–FRO6 Module Integrates the Control of Leaf Senescence and Flowering in Arabidopsis

open access: yesPlant, Cell &Environment, Volume 49, Issue 9, Page 7191-7209, September 2026.
ABSTRACT Plants coordinate major developmental transitions by integrating intrinsic genetic programs with environmental signals, where nutrient availability serves as a critical external factor shaping growth and fitness. Iron (Fe), an essential micronutrient for cellular respiration and photosynthesis, is strictly regulated through sophisticated ...
Hyunsu Park   +8 more
wiley   +1 more source

The Painterly Materiality of Clouds in Antony and Cleopatra and Hamlet

open access: yesRenaissance Studies, Volume 40, Issue 4, Page 589-608, September 2026.
Abstract This article examines the cloud‐gazing scenes in Antony and Cleopatra and Hamlet through the lens of early modern artistic theory and material practices, particularly the art of limning. Building upon existing philosophical and poetic interpretations of Shakespearean clouds as metaphors for ephemerality and memory, the essay argues that the ...
Anne‐Valérie Dulac
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, Volume 20, Issue 8, Page 1963-1985, August 2026.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Genome-wide chromosome architecture prediction reveals biophysical principles underlying gene structure. [PDF]

open access: yesCell Genom
Chiang M   +6 more
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, Volume 20, Issue 8, Page 2114-2128, August 2026.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Beyond Binary: Cardiac Patterning as Probabilistic Fate Restriction

open access: yesBioEssays, Volume 48, Issue 8, August 2026.
Are cardiac progenitors committed to fixed lineages, or do they carry probability distributions over heart regions in the epiblast that resolve during gastrulation? Reanalyzing mouse retrospective clonal data, we find no single lineage tree, instead 361 distinct restriction topologies, consistent with a probabilistic model where epiblast position set ...
Kenzo Ivanovitch
wiley   +1 more source

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