Topoisomerase inhibitory activity of ethanolic extracts from botanicals <i>Coptis chinensis</i> and <i>Salvia officinalis</i>. [PDF]
Ingersoll W +4 more
europepmc +1 more source
ABSTRACT Cancer ranks as a leading cause of death worldwide, demanding new affordable therapies. Nature offers a diverse array of bioactive scaffolds, including 1,4‐naphthoquinone, which serves as a precursor for numerous natural and synthetic compounds with potent antitumor properties.
Eduardo Angulo‐Elizari +7 more
wiley +1 more source
Structural insights into fungal and human topoisomerase II with implications for in silico antifungal drug design. [PDF]
Sappati S +3 more
europepmc +1 more source
Improving mandibular reconstruction by using topology optimization, patient specific design and additive manufacturing?-A biomechanical comparison against miniplates on human specimen. [PDF]
Lang JJ +11 more
europepmc +1 more source
Generation and Characterization of a Rdh1‐iCre Line to Study Uterine Glandular Biology
ABSTRACT The uterus is an essential organ for fetal development in most mammals. Uterine glands, highly conserved structures in the mammalian uterus, play critical roles in the establishment and maintenance of pregnancy and have been implicated in the pathogenesis of uterine diseases, including endometrial cancer and endometriosis.
Mana Ohtomo +11 more
wiley +1 more source
Soil nutrients and microbial community resistant to patch‐burn grazing in southwestern North Dakota
Abstract Patch‐burn grazing uses the interactive effects of prescribed fire and herbivory to increase heterogeneity in aboveground ecosystem properties. Understanding how management that targets aboveground heterogeneity translates to soil properties and processes provides an important whole‐system context for practitioners.
Jonathan W. Spiess +5 more
wiley +1 more source
Experimental localization of metal-binding sites reveals the role of metal ions in type II DNA topoisomerases. [PDF]
Wang B +9 more
europepmc +1 more source
Impact of an extreme storm event on a multiple intertidal barred coastal system
Extreme storms do not necessarily cause extreme coastal erosion. Integrated DGPS surveys and SWAN nearshore wave modelling reveal that Storm Barra's peak coincided with a low‐tide stage, allowing multiple intertidal bars (MITBs) to dissipate incoming wave energy before it reached Dundrum Bay's shoreline, highlighting the combined role of tidal stage ...
Melanie Biausque +4 more
wiley +1 more source
From Binary to Ternary Hydrogen-Bonded Solids with Anisotropic Thermal Expansion. [PDF]
Ma L, Kelley SP, Hutchins KM.
europepmc +1 more source

