High-Risk neuroblastoma therapeutics Topotecan and 13-cis-Retinoic acid modulate autophagy and induce DNA damage response in hematopoietic stem cells and monocytes. [PDF]
Lázničková P +5 more
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A New Era of Treatment Sequencing in Platinum-Resistant Ovarian Cancer: Integrating Immunotherapy, Antibody-Drug Conjugates, and Targeted Therapies. [PDF]
Mabuchi S, Kusakabe A, Takimoto Y.
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Inclusion of JNK-independent drugs within multiagent chemotherapy improves response in relapsed high-risk neuroblastoma. [PDF]
Han JZR +19 more
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Treatment Sequencing in Platinum-Resistant Epithelial Ovarian Cancer After MIRASOL, KEYNOTE-B96, and ROSELLA. [PDF]
Liu Y, Xu M, Ma J, Zhu Y, Gao M.
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A Real-World Data Analysis of Topotecan in the FDA Adverse Event Reporting System (FAERS) Database
Expert Opinion on Drug Metabolism and Toxicology, 2023Objectives The objective of this study was to monitor and identify adverse events (AEs) associated with topotecan, a medication used for the treatment of solid tumors, in order to improve patient safety and guide medication usage.
Bin Zhao, Zheng Wan
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To study topotecan–DNA interaction and topotecan determination with a modified carbon paste electrode (CPE), a new electrochemical biosensor is introduced.
Somayeh Tajik +2 more
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Intravitreal Topotecan 90 µg for Recurrent Solid Retinoblastoma Tumors Is Effective and Not Toxic.
Journal of pediatric ophthalmology and strabismus, 2023The authors report on the safety and efficacy of 90 µg/0.18 cc of intravitreal topotecan for recurrent solid retinal tumors in retinoblastoma. Topotecan 90 µg was injected intravitreally in three retinoblastoma cases that progressed after prior therapy ...
D. Abramson, J. Francis
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